This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Type 2 diabetes has reached epidemic proportions in the United States, affecting an increasing number of adults, with minority groups, such as African Americans disproportionately affected. The standard, first stage of treating diabetes is to initiate lifestyle modifications such as diet and physical activity. Evidence from clinical controlled trials suggests that the successful application of MNT alone lowers glycated hemoglobin (HbA1c) levels by 1% to 2% in adults with type 2 diabetes. This is similar to what has been demonstrated by first line oral hypoglycemic agents such as metformin and sulfonylureas. When glycemic control worsens, either due to dietary non-adherence or the natural progression of diabetes, medications to control diabetes are often added with waning attention given to diet management. The purpose of this research is to determine the effect of MNT, in combination with diabetes medication, on HbA1c levels in women with type 2 diabetes. This effect will be determined by comparing African American and white women randomized to receive drug treatment alone or in combination with MNT over a study period of 4 months.
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