The investigators will develop and demonstrate the efficacy of a set of original cardiovascular disease (CVD) nutrition education materials designed to reduce intake of sodium (Na), fat and cholesterol, and determine which will be appropriate for urban, black adults with 5th to 8th grade reading levels. The investigators will design materials to accomplish the objectives of conventional nutrition education and behavior change programs, but avoid the usual dependency of traditional programs on strategies that require a high level of reading and arithmetic. Guiding principles will be: 1) the need to identify the food- related conceptual, cultural, and social frameworks of members of the target audience; and 2) to develop a program that builds upon already- developed, alternative communication and coping skills. Using a randomized two-group design and a 12-24 month follow-up, serum cholesterol, and blood pressure levels of persons (n=200) counseled with the CARDES program will be compared with values for a control group (n=200) receiving usual care. Process measures will describe adherence outcomes and determinants. Secondary outcomes related to CVD risk factor status also will be evaluated. Prior to the evaluation, a pilot study determined best sequence for delivering the information related to dietary change (i.e., Na first, fat/cholesterol first, or concurrently) and the potential utility of CARDES with other black populations with low literacy skills was assessed. This project should lead to an improved capability for reducing risks related to hypertension and elevated cholesterol in black populations by enabling interventions to reach the subpopulations that are only marginally literate.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
1M01RR010284-01A1
Application #
5225836
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Christensen, Kurt D; Uhlmann, Wendy R; Roberts, J Scott et al. (2018) A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone. Genet Med 20:132-141
Doumatey, Ayo P; He, William J; Gaye, Amadou et al. (2018) Circulating MiR-374a-5p is a potential modulator of the inflammatory process in obesity. Sci Rep 8:7680
Guan, Yue; Roter, Debra L; Wolff, Jennifer L et al. (2018) The impact of genetic counselors' use of facilitative strategies on cognitive and emotional processing of genetic risk disclosure for Alzheimer's disease. Patient Educ Couns 101:817-823
Mullins, Tanya L Kowalczyk; Li, Su X; Bethel, James et al. (2018) Sexually transmitted infections and immune activation among HIV-infected but virally suppressed youth on antiretroviral therapy. J Clin Virol 102:7-11
Faruque, Mezbah U; Chen, Guanjie; Doumatey, Ayo P et al. (2017) Transferability of genome-wide associated loci for asthma in African Americans. J Asthma 54:1-8
Guan, Yue; Roter, Debra L; Erby, Lori H et al. (2017) Disclosing genetic risk of Alzheimer's disease to cognitively impaired patients and visit companions: Findings from the REVEAL Study. Patient Educ Couns 100:927-935
Nandakumar, Priyanka; Lee, Dongwon; Richard, Melissa A et al. (2017) Rare coding variants associated with blood pressure variation in 15?914 individuals of African ancestry. J Hypertens 35:1381-1389
Lieberman, Richard; Armeli, Stephen; Scott, Denise M et al. (2016) FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students. Am J Med Genet B Neuropsychiatr Genet 171:879-87
Christensen, Kurt D; Roberts, J Scott; Whitehouse, Peter J et al. (2016) Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial. Ann Intern Med 164:155-63
Armeli, Stephen; O'Hara, Ross E; Covault, Jon et al. (2016) Episode-specific drinking-to-cope motivation and next-day stress-reactivity. Anxiety Stress Coping 29:673-84

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