Abstract

Osteoporosis is a prevalent disease with widespread devastating clinical consequences. Treatment to date has involved agents which by and large prevent bone loss rather than induce new bone formation; thus we have obvious limitations in treatment options for the patient with established disease. No safe effective bone forming agent has yet to be approved for the treatment of this disease. The purpose of this study is to test the safety and efficacy of Low Dose Doxycycline for stimulation of bone formation in postmenopausal women with osteoporosis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR010710-02
Application #
6286423
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1998-06-04
Project End
2001-11-30
Budget Start
Budget End
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
State University New York Stony Brook
Department
Type
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794

  Publications

Lima, Fabio V; Gruberg, Luis; Aslam, Usman et al. (2018) The impact of unfractionated heparin or bivalirudin on patients with stable coronary artery disease undergoing percutaneous coronary intervention. J Interv Cardiol 31:177-184
Cornelius, Talea; Birk, Jeffrey L; Edmondson, Donald et al. (2018) The joint influence of emotional reactivity and social interaction quality on cardiovascular responses to daily social interactions in working adults. J Psychosom Res 108:70-77
Edmondson, Donald; Sumner, Jennifer A; Kronish, Ian M et al. (2018) The Association of Posttraumatic Stress Disorder With Clinic and Ambulatory Blood Pressure in Healthy Adults. Psychosom Med 80:55-61
Farmer, Cristan A; Epstein, Jeffery N; Findling, Robert L et al. (2017) Risperidone Added to Psychostimulant in Children with Severe Aggression and Attention-Deficit/Hyperactivity Disorder: Lack of Effect on Attention and Short-Term Memory. J Child Adolesc Psychopharmacol 27:117-124
Findling, Robert L; Townsend, Lisa; Brown, Nicole V et al. (2017) The Treatment of Severe Childhood Aggression Study: 12 Weeks of Extended, Blinded Treatment in Clinical Responders. J Child Adolesc Psychopharmacol 27:52-65
Wang, Y Claire; Shimbo, Daichi; Muntner, Paul et al. (2017) Prevalence of Masked Hypertension Among US Adults With Nonelevated Clinic Blood Pressure. Am J Epidemiol 185:194-202
Jurgens, Corrine Y; Lee, Christopher S; Riegel, Barbara (2017) Psychometric Analysis of the Heart Failure Somatic Perception Scale as a Measure of Patient Symptom Perception. J Cardiovasc Nurs 32:140-147
Parisette-Sparks, Alyssa; Bufferd, Sara J; Klein, Daniel N (2017) Parental Predictors of Children's Shame and Guilt at Age 6 in a Multimethod, Longitudinal Study. J Clin Child Adolesc Psychol 46:721-731
Barrios, Chelsey S; Bufferd, Sara J; Klein, Daniel N et al. (2017) The interaction between parenting and children's cortisol reactivity at age 3 predicts increases in children's internalizing and externalizing symptoms at age 6. Dev Psychopathol 29:1319-1331
Broderick, Joan E; Keefe, Francis J; Schneider, Stefan et al. (2016) Cognitive behavioral therapy for chronic pain is effective, but for whom? Pain 157:2115-23

Showing the most recent 10 out of 283 publications