Diet is the cornerstone of therapy for hypertension, dyslipidemia and diabetes mellitus; these dietary modifications include reduced intake of total and saturated fat, cholesterol, sodium and refined sugars, and attaining adequate intakes of minerals, vitamins, fiber and complex carbohydrates. Unfortunately, it is difficult for many people to change their diets. Thus, non-compliance with therapeutic dietary regimens remains a major obstacle in achieving improvements in cardiovascular disease (CVD) morbidity and mortality. The difficulties in complying with dietary recommendations come from a number of areas. Understanding, planning and implementing diets that meet the guidelines recommended for the control of diet responsive chronic diseases is a complex task that requires considerable effort on the patient's part. To meet the guidelines, patients must calculate the nutrient content of the foods they eat, select a balance of foods that provide the right combination of nutrients, determine appropriate portion sizes, and then prepare the food in specific ways. To address the challenge of implementing the diverse dietary recommendations commonly prescribed for patients at increased risk of cardiovascular disease, the principles of nutrition science and procedures of food technology were combined to develop a balanced and convenient total nutrition food program. Three short term clinical trials were performed to test the acceptability and effectiveness of this program These clinical trials demonstrated that it is feasible for free-living individuals to follow (for a short time) a food plan that provides essentially all the RDA's of the National Academy of Sciences while meeting the nutritional recommendations for cardiovascular risk reduction of major U.S. health organizations. This intervention, although of limited duration, resulted in improvements in multiple cardiovascular risk factors including hypertension, hyperlipidemia, hyperinsulinemia and body weight. The purpose of the current study is to test the acceptability and effectiveness of this program in a long term clinical trial. This study is designed to: measure the acceptability of following a long-term Meal Program and determine the difference between two dietary intervention groups that follow a therapeutically prescribed meal program over 52 weeks by either the usual care therapeutic diet or a Meal Program. The variables to be studies include: body weight, blood pressure, plasma lipids, insulin, hemoglobin A1C, vitamin levels, urine electrolytes, serum iron and ferritin, quality of life, diet satisfaction, and compliance with diet.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Type
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Lieberman, Jay L; DE Souza, Mary Jane; Wagstaff, David A et al. (2018) Menstrual Disruption with Exercise Is Not Linked to an Energy Availability Threshold. Med Sci Sports Exerc 50:551-561
Zhang, Lijun; Wang, Ming; Sterling, Nicholas W et al. (2018) Cortical Thinning and Cognitive Impairment in Parkinson's Disease without Dementia. IEEE/ACM Trans Comput Biol Bioinform 15:570-580
Rossi, Alexander; Berger, Kristin; Chen, Honglei et al. (2018) Projection of the prevalence of Parkinson's disease in the coming decades: Revisited. Mov Disord 33:156-159
Lee, Soomi; Martire, Lynn M; Damaske, Sarah A et al. (2018) Covariation in couples' nightly sleep and gender differences. Sleep Health 4:201-208
Almeida, David M; Lee, Soomi; Walter, Kimberly N et al. (2018) The effects of a workplace intervention on employees' cortisol awakening response. Community Work Fam 21:151-167
Liu, Guodong; Sterling, Nicholas W; Kong, Lan et al. (2017) Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database. Mov Disord 32:913-917
Sterling, Nicholas W; Du, Guangwei; Lewis, Mechelle M et al. (2017) Cortical gray and subcortical white matter associations in Parkinson's disease. Neurobiol Aging 49:100-108
Berryman, Claire E; Fleming, Jennifer A; Kris-Etherton, Penny M (2017) Inclusion of Almonds in a Cholesterol-Lowering Diet Improves Plasma HDL Subspecies and Cholesterol Efflux to Serum in Normal-Weight Individuals with Elevated LDL Cholesterol. J Nutr 147:1517-1523
Calhoun, Susan L; Fernandez-Mendoza, Julio; Vgontzas, Alexandros N et al. (2017) Behavioral Profiles Associated with Objective Sleep Duration in Young Children with Insomnia Symptoms. J Abnorm Child Psychol 45:337-344
Quick, Virginia; Byrd-Bredbenner, Carol; Shoff, Suzanne et al. (2016) Relationships of Sleep Duration With Weight-Related Behaviors of U.S. College Students. Behav Sleep Med 14:565-80

Showing the most recent 10 out of 645 publications