The use of rHuEpo to treat anemia in patients with ESRD has been a major advance in the care of these patients. Such therapy is frequently associated with the development of functional iron deficiency due to rapid transfer of bone marrow iron stores to euthroid progenitor cells. Iron therapy in dialysis patients is most commonly administered orally. However, patient non-compliance, GI side effects, poor GI absorption, and drug interaction are the limiting factors in the efficacy of oral iron therapy. To eliminate these factors, the i.v. route has become the preferred method of iron supplementation in chronic hemodialysis patients. Alternatively in some situations, the i.m. route has been successfully used. In both these parenteral methods, several doses of small quantities, usually 100mg of iron dextran are administered on successive days or weeks. neither of these methods however, is an attractive alternative in ambulatory PD patients. Recently, a retrospective study showed the effective use of bolus iron dextran (1 gram) infusion in the treatment of iron deficiency anemia in PD patients receiving rHuEpo. The purpose of this study is therefore to compare the efficacy of single bolus iron dextran (1 gram) infusion and conventional oral iron in the treatment of iron deficiency anemia in PD patients receiving rHuEpo.
| Lieberman, Jay L; DE Souza, Mary Jane; Wagstaff, David A et al. (2018) Menstrual Disruption with Exercise Is Not Linked to an Energy Availability Threshold. Med Sci Sports Exerc 50:551-561 |
| Zhang, Lijun; Wang, Ming; Sterling, Nicholas W et al. (2018) Cortical Thinning and Cognitive Impairment in Parkinson's Disease without Dementia. IEEE/ACM Trans Comput Biol Bioinform 15:570-580 |
| Rossi, Alexander; Berger, Kristin; Chen, Honglei et al. (2018) Projection of the prevalence of Parkinson's disease in the coming decades: Revisited. Mov Disord 33:156-159 |
| Lee, Soomi; Martire, Lynn M; Damaske, Sarah A et al. (2018) Covariation in couples' nightly sleep and gender differences. Sleep Health 4:201-208 |
| Almeida, David M; Lee, Soomi; Walter, Kimberly N et al. (2018) The effects of a workplace intervention on employees' cortisol awakening response. Community Work Fam 21:151-167 |
| Liu, Guodong; Sterling, Nicholas W; Kong, Lan et al. (2017) Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database. Mov Disord 32:913-917 |
| Sterling, Nicholas W; Du, Guangwei; Lewis, Mechelle M et al. (2017) Cortical gray and subcortical white matter associations in Parkinson's disease. Neurobiol Aging 49:100-108 |
| Berryman, Claire E; Fleming, Jennifer A; Kris-Etherton, Penny M (2017) Inclusion of Almonds in a Cholesterol-Lowering Diet Improves Plasma HDL Subspecies and Cholesterol Efflux to Serum in Normal-Weight Individuals with Elevated LDL Cholesterol. J Nutr 147:1517-1523 |
| Calhoun, Susan L; Fernandez-Mendoza, Julio; Vgontzas, Alexandros N et al. (2017) Behavioral Profiles Associated with Objective Sleep Duration in Young Children with Insomnia Symptoms. J Abnorm Child Psychol 45:337-344 |
| Lewis, Mechelle M; Flynn, Michael R; Lee, Eun-Young et al. (2016) Longitudinal T1 relaxation rate (R1) captures changes in short-term Mn exposure in welders. Neurotoxicology 57:39-44 |
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