This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Purpose: To quantify core-to-skin thermal resistance during VC as a function of age and lean body mass, and refine models of human heat transfer in cold environments. Hypothesis a. The solution of heat balance equations will yield a lower derived core-to-skin thermal resistance (tissue insulation, IT) for older compared to young subjects of similar size and body composition. Hypothesis b. Controlling for age, subjects with decreased body mass and/or decreased lean body mass will exhibit a lower maximal IT. Age-groups consist of normal and lean/sarcopenic individuals. Young subjects are defined as 18-30 years; older subjects are 65-85 years old. Subjects are instrumented for measurement of the body's core and skin temperatures, forearm blood flow (FBF), skin blood flow (SkBF), blood pressure, and heart rate. Expired air is collected for the last 5 min of every 20 min period and analyzed for volume, O2 concentration, and CO2 concentration. After a 20-min baseline period at a dry bulb air temperature (Tdb) = 23 oC (73.4 degrees F) and relative humidity (RH) = 30%], Tdb are decreased to 12 degrees C (53.6 oF) and maintained for 40 minutes. Then, Tdb is lowered at a rate of 1degree C (1.8 degrees F)/20 min, until the onset of shivering or the subject wishes to discontinue. Shivering is determined by visual observation and self-report. During a 30-min recovery, the area around the laser Doppler probes is heated.
| Lieberman, Jay L; DE Souza, Mary Jane; Wagstaff, David A et al. (2018) Menstrual Disruption with Exercise Is Not Linked to an Energy Availability Threshold. Med Sci Sports Exerc 50:551-561 |
| Zhang, Lijun; Wang, Ming; Sterling, Nicholas W et al. (2018) Cortical Thinning and Cognitive Impairment in Parkinson's Disease without Dementia. IEEE/ACM Trans Comput Biol Bioinform 15:570-580 |
| Rossi, Alexander; Berger, Kristin; Chen, Honglei et al. (2018) Projection of the prevalence of Parkinson's disease in the coming decades: Revisited. Mov Disord 33:156-159 |
| Lee, Soomi; Martire, Lynn M; Damaske, Sarah A et al. (2018) Covariation in couples' nightly sleep and gender differences. Sleep Health 4:201-208 |
| Almeida, David M; Lee, Soomi; Walter, Kimberly N et al. (2018) The effects of a workplace intervention on employees' cortisol awakening response. Community Work Fam 21:151-167 |
| Liu, Guodong; Sterling, Nicholas W; Kong, Lan et al. (2017) Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database. Mov Disord 32:913-917 |
| Sterling, Nicholas W; Du, Guangwei; Lewis, Mechelle M et al. (2017) Cortical gray and subcortical white matter associations in Parkinson's disease. Neurobiol Aging 49:100-108 |
| Berryman, Claire E; Fleming, Jennifer A; Kris-Etherton, Penny M (2017) Inclusion of Almonds in a Cholesterol-Lowering Diet Improves Plasma HDL Subspecies and Cholesterol Efflux to Serum in Normal-Weight Individuals with Elevated LDL Cholesterol. J Nutr 147:1517-1523 |
| Calhoun, Susan L; Fernandez-Mendoza, Julio; Vgontzas, Alexandros N et al. (2017) Behavioral Profiles Associated with Objective Sleep Duration in Young Children with Insomnia Symptoms. J Abnorm Child Psychol 45:337-344 |
| Quick, Virginia; Byrd-Bredbenner, Carol; Shoff, Suzanne et al. (2016) Relationships of Sleep Duration With Weight-Related Behaviors of U.S. College Students. Behav Sleep Med 14:565-80 |
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