This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Early Childhood Caries (ECC), or nursing caries, is a form of decay of the primary dentition that is distinguished by the specificity of tooth surfaces involved and the rapid progression of carious lesions on those surfaces that are considered, otherwise, to be at low risk to decay. The likely consequences of untreated ECC on the overall health of the child have not been investigated in a formal analytical epidemiological study. This study will examine the impact of severe early childhood caries (S-ECC) and of subsequent, comprehensive dental intervention on weight. The study will compare children with S-ECC who have no other chronic medical problems and who have not previously received invasive dental treatment with healthy, caries free subjects, matched by age (in months), gender and race.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR020359-04
Application #
7717163
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2007-12-01
Project End
2008-11-30
Budget Start
2007-12-01
Budget End
2008-11-30
Support Year
4
Fiscal Year
2008
Total Cost
$36,966
Indirect Cost
Name
Children's Research Institute
Department
Type
DUNS #
143983562
City
Washington
State
DC
Country
United States
Zip Code
20010
Sady, Maegan D; Vaughan, Christopher G; Gioia, Gerard A (2018) Measuring Dynamic Symptom Response in Concussion: Children's Exertional Effects Rating Scale. J Head Trauma Rehabil :
Mullins, Tanya L Kowalczyk; Li, Su X; Bethel, James et al. (2018) Sexually transmitted infections and immune activation among HIV-infected but virally suppressed youth on antiretroviral therapy. J Clin Virol 102:7-11
Kahn, Jessica A; Xu, Jiahong; Kapogiannis, Bill G et al. (2017) Brief Report: Antibody Responses to Quadrivalent HPV Vaccination in HIV-Infected Young Women as Measured by Total IgG and Competitive Luminex Immunoassay. J Acquir Immune Defic Syndr 75:241-245
Smits, Anne; van den Anker, John N; Allegaert, Karel (2017) Clinical pharmacology of analgosedatives in neonates: ways to improve their safe and effective use. J Pharm Pharmacol 69:350-360
Newport, Elissa L; Landau, Barbara; Seydell-Greenwald, Anna et al. (2017) Revisiting Lenneberg's Hypotheses About Early Developmental Plasticity: Language Organization After Left-Hemisphere Perinatal Stroke. Biolinguistics (Nicos) 11:407-422
Gioia, Gerard A (2016) Medical-School Partnership in Guiding Return to School Following Mild Traumatic Brain Injury in Youth. J Child Neurol 31:93-108
Terwilliger, Virginia K; Pratson, Lincoln; Vaughan, Christopher G et al. (2016) Additional Post-Concussion Impact Exposure May Affect Recovery in Adolescent Athletes. J Neurotrauma 33:761-5
Ruan, Alexandra; Tobin, Nicole H; Mulligan, Kathleen et al. (2016) Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021. J Acquir Immune Defic Syndr 72:372-5
Orrock, Janet E; Panchapakesan, Karuna; Vezina, Gilbert et al. (2016) Association of brain injury and neonatal cytokine response during therapeutic hypothermia in newborns with hypoxic-ischemic encephalopathy. Pediatr Res 79:742-7
Sepeta, Leigh N; Berl, Madison M; Wilke, Marko et al. (2016) Age-dependent mesial temporal lobe lateralization in language fMRI. Epilepsia 57:122-30

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