Abstract

This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The ORIGIN Study will evaluate whether people with IGT, IFG, and early type 2 diabetes who are at high risk for macrovascular events can be safely treated wih insulin glargine to near normal levels of blood glucose. It is hypothesized that this treatment will reduce their risk for future macrovascular and microvascular events compared to a control group who will be followed and treated according to normal guidelines.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR023942-02
Application #
7719034
Study Section
Special Emphasis Panel (ZRR1-CR-3 (01))
Project Start
2008-04-01
Project End
2009-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
2
Fiscal Year
2008
Total Cost
$33,533
Indirect Cost

  Institution

Name
Georgetown University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057

  Publications

Goldman, Noreen; Glei, Dana A; Weinstein, Maxine (2018) Declining mental health among disadvantaged Americans. Proc Natl Acad Sci U S A 115:7290-7295
Nersesian, Paula V; Han, Hae-Ra; Yenokyan, Gayane et al. (2018) Loneliness in middle age and biomarkers of systemic inflammation: Findings from Midlife in the United States. Soc Sci Med 209:174-181
Glei, Dana A; Goldman, Noreen; Ryff, Carol D et al. (2018) Physical Function in U.S. Older Adults Compared With Other Populations: A Multinational Study. J Aging Health :898264318759378
Stephan, Yannick; Sutin, Angelina R; Bayard, Sophie et al. (2018) Personality and sleep quality: Evidence from four prospective studies. Health Psychol 37:271-281
Liebzeit, Daniel; Phelan, Cynthia; Moon, Chooza et al. (2017) Rest-Activity Patterns in Older Adults with Heart Failure and Healthy Older Adults. J Aging Phys Act 25:116-122
Chirinos, Diana A; Murdock, Kyle W; LeRoy, Angie S et al. (2017) Depressive symptom profiles, cardio-metabolic risk and inflammation: Results from the MIDUS study. Psychoneuroendocrinology 82:17-25
Robinette, Jennifer W; Charles, Susan T; Gruenewald, Tara L (2017) Neighborhood Socioeconomic Status and Health: A Longitudinal Analysis. J Community Health 42:865-871
Sloan, Richard P; Schwarz, Emilie; McKinley, Paula S et al. (2017) Vagally-mediated heart rate variability and indices of well-being: Results of a nationally representative study. Health Psychol 36:73-81
Chung, Joon (2017) Social support, social strain, sleep quality, and actigraphic sleep characteristics: evidence from a national survey of US adults. Sleep Health 3:22-27
Glei, Dana A; Goldman, Noreen; Ryff, Carol D et al. (2017) Can we determine whether physical limitations are more prevalent in the US than in countries with comparable life expectancy? SSM Popul Health 3:808-813

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