This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a pilot study to determine how well biomarkers in serum (TNF-alpha, MCP-1, IL-12, sIL-2R, lysozyme, neopterin), urine (neopterin), and bronchoalveolar lavage fluid, when available, correlate with standard clinical indices of active sarcoid disease (signs, symptoms, PFT's, x-rays, sarcoidosis health-related QOL). Samples will also be saved for proteomic studies.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR023942-03
Application #
7951987
Study Section
Special Emphasis Panel (ZRR1-CR-3 (01))
Project Start
2009-04-01
Project End
2010-03-31
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
3
Fiscal Year
2009
Total Cost
$8,632
Indirect Cost
Name
Georgetown University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Goldman, Noreen; Glei, Dana A; Weinstein, Maxine (2018) Declining mental health among disadvantaged Americans. Proc Natl Acad Sci U S A 115:7290-7295
Nersesian, Paula V; Han, Hae-Ra; Yenokyan, Gayane et al. (2018) Loneliness in middle age and biomarkers of systemic inflammation: Findings from Midlife in the United States. Soc Sci Med 209:174-181
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Chung, Joon (2017) Social support, social strain, sleep quality, and actigraphic sleep characteristics: evidence from a national survey of US adults. Sleep Health 3:22-27
Glei, Dana A; Goldman, Noreen; Ryff, Carol D et al. (2017) Can we determine whether physical limitations are more prevalent in the US than in countries with comparable life expectancy? SSM Popul Health 3:808-813

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