Project Start
1993-05-16
Project End
1998-05-29
Budget Start
1998-05-15
Budget End
1998-05-29
Support Year
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Cornell University
Department
Chemistry
Type
Schools of Veterinary Medicine
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Casey, John L; Tennant, Bud C; Gerin, John L (2006) Genetic changes in hepatitis delta virus from acutely and chronically infected woodchucks. J Virol 80:6469-77
Casey, John; Cote, Paul J; Toshkov, Illia A et al. (2005) Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks. Antimicrob Agents Chemother 49:4396-9
Jacob, James R; Sterczer, Agnes; Toshkov, Ilia A et al. (2004) Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors. Hepatology 39:1008-16
Tatti, Kathleen M; Korba, Brent E; Stang, Heather L et al. (2002) Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine. Antiviral Res 55:141-50
Menne, Stephan; Roneker, Carol A; Roggendorf, Michael et al. (2002) Deficiencies in the acute-phase cell-mediated immune response to viral antigens are associated with development of chronic woodchuck hepatitis virus infection following neonatal inoculation. J Virol 76:1769-80
Nagy, Tamas; McDonough, Sean P; Erb, Hollis N et al. (2002) Lymphosarcoma in the laboratory woodchuck (Marmota monax). Comp Med 52:152-9
Menne, Stephan; Roneker, Carol A; Korba, Brent E et al. (2002) Immunization with surface antigen vaccine alone and after treatment with 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)-uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection. J Virol 76:5305-14
Hurwitz, Selwyn J; Tennant, Bud C; Korba, Brent E et al. (2002) Viral pharmacodynamic model for (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine (emtricitabine) in chronically infected woodchucks. Antivir Chem Chemother 13:165-76
Sahu, Gautam Kumar; Tai, Pei-Ching; Chatterjee, Soma Banerjee et al. (2002) Out-of-frame versus in-frame core internal deletion variants of human and woodchuck hepatitis B viruses. Virology 292:35-43
Concannon, P; Levac, K; Rawson, R et al. (2001) Seasonal changes in serum leptin, food intake, and body weight in photoentrained woodchucks. Am J Physiol Regul Integr Comp Physiol 281:R951-9

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