Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM037614-005
Application #
3611010
Study Section
Project Start
1983-05-21
Project End
1986-04-04
Budget Start
1985-04-12
Budget End
1986-04-04
Support Year
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Parke Davis Pharmaceutical Research Div
Department
Type
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48105
Showalter, H D; Bunge, R H; French, J C et al. (1992) Improved production of pentostatin and identification of fermentation cometabolites. J Antibiot (Tokyo) 45:1914-8
Jackson, R C; Boritzki, T J; Besserer, J A et al. (1987) Biochemical pharmacology and experimental chemotherapy studies with guanine-7-oxide, a novel purine antibiotic. Adv Enzyme Regul 26:301-16
Jackson, R C; Leopold, W R; Ross, D A (1986) The biochemical pharmacology of (2'-R)-chloropentostatin, a novel inhibitor of adenosine deaminase. Adv Enzyme Regul 25:125-39
Roberts, B J; Hamelehle, K L; Sebolt, J S et al. (1986) In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721). Cancer Chemother Pharmacol 16:95-101
Wilton, J H; Rithner, C D; Hokanson, G C et al. (1986) A novel sulfur-containing hexose from the antitumor antibiotics, PD 114,759 and PD 115,028. J Antibiot (Tokyo) 39:1349-50
Smitka, T A; Bunge, R H; Wilton, J H et al. (1986) PD 116,152, a new phenazine antitumor antibiotic. Structure and antitumor activity. J Antibiot (Tokyo) 39:800-3
Kern, D L; Schaumberg, J P; Hokanson, G C et al. (1986) PD 116,779, a new antitumor antibiotic of the benz[a]anthraquinone class. J Antibiot (Tokyo) 39:469-70
Hurley, T R; Smitka, T A; Wilton, J H et al. (1986) PD 113,618 and PD 118,309, new pactamycin analogs. J Antibiot (Tokyo) 39:1086-91
Hurley, T R; Bunge, R H; Willmer, N E et al. (1986) PD 124,895 and PD 124,966, two new antitumor antibiotics. J Antibiot (Tokyo) 39:1651-6
Tunac, J B; Graham, B D; Mamber, S W et al. (1985) Potent antitumor antibiotic complex: PD 114,759, PD 115,028, PD 119,707, and PD 119,193. J Antibiot (Tokyo) 38:1337-43

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