Abstract

The NCI sponsored U.S.-Finland Studies in Nutrition and Cancer is a three- study project. The main thrust of the project is the beta-carotene, vitamin E intervention trial, which will involve a twelve month pilot phase and up to two years of subject accrual, with intervention for 5 years there-after. It is anticipated that many of the personnel, support services and coordinating facilities for this clinical trial will also be used to conduct the two other studies. The phasing in of these studies should take place as early as possible during the contract period. Each study is designed to yield valuable data in the area of nutritional effects on cancer development and the acquisition of these data is the project's primary goal.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Prevention And Control (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CN045165-020
Application #
2302575
Study Section
Project Start
1984-03-31
Project End
Budget Start
1992-09-30
Budget End
1993-03-31
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
National Public Health Institute
Department
Type
DUNS #
City
Helsinki
State
Country
Finland
Zip Code
00300

  Publications

Feng, Yun; Wang, Yanru; Liu, Hongliang et al. (2017) Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium. Sci Rep 7:825
Murphy, Gwen; Abnet, Christian C; Choo-Wosoba, Hyoyoung et al. (2017) Serum gastrin and cholecystokinin are associated with subsequent development of gastric cancer in a prospective cohort of Finnish smokers. Int J Epidemiol 46:914-923
Pan, Yongchu; Liu, Hongliang; Wang, Yanru et al. (2017) Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs. Sci Rep 7:44634
Yin, Jieyun; Liu, Hongliang; Liu, Zhensheng et al. (2017) Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. Mol Carcinog 56:1663-1672
Zhou, Fei; Wang, Yanru; Liu, Hongliang et al. (2017) Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs. Mol Carcinog 56:1227-1238
Nogueira, Leticia M; Newton, Christina C; Pollak, Michael et al. (2017) Serum C-peptide, Total and High Molecular Weight Adiponectin, and Pancreatic Cancer: Do Associations Differ by Smoking? Cancer Epidemiol Biomarkers Prev 26:914-922
Law, Philip J; Berndt, Sonja I; Speedy, Helen E et al. (2017) Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. Nat Commun 8:14175
Patel, Yesha M; Park, Sunghim L; Han, Younghun et al. (2016) Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. Cancer Res 76:5768-5776
Kang, Xiaozheng; Liu, Hongliang; Onaitis, Mark W et al. (2016) Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls. Carcinogenesis 37:280-289
Dunkhase, Eva; Ludwig, Kerstin U; Knapp, Michael et al. (2016) Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data. Genom Data 10:22-9

Showing the most recent 10 out of 240 publications