Abstract

The purpose of this program is to support a fully operational liver transplantation database in order to collect data from patients and donors in the United States who have been evaluated and have had liver transplantation for a variety of end stage liver diseases. The Transplantation Centers will be responsible for patient recruitment and for collecting the required data and submitting that data to the Coordinating Center. The Transplantation Centers will be expected to recruit a sufficient number of patients evaluated for liver transplantation to provide the database with at least one liver transplantation patient a week or at least 50 liver transplantation patients a year. The Centers will also be responsible for collecting data on the donor and on the harvesting procedure.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research and Development Contracts (N01)
Project #
N01DK002253-005
Application #
2307099
Study Section
Project Start
1990-01-01
Project End
1995-03-31
Budget Start
1991-09-30
Budget End
1994-03-31
Support Year
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905

  Publications

Everhart, J E; Wei, Y; Eng, H et al. (1999) Recurrent and new hepatitis C virus infection after liver transplantation. Hepatology 29:1220-6
Germer, J J; Rys, P N; Thorvilson, J N et al. (1999) Determination of hepatitis C virus genotype by direct sequence analysis of products generated with the Amplicor HCV test. J Clin Microbiol 37:2625-30
Showstack, J; Katz, P P; Lake, J R et al. (1999) Resource utilization in liver transplantation: effects of patient characteristics and clinical practice. NIDDK Liver Transplantation Database Group. JAMA 281:1381-6
Katz, P P; Showstack, J A; Lake, J R et al. (1999) Methods to estimate and analyze medical care resource use. An example from liver transplantation. Int J Technol Assess Health Care 15:366-79
Deschenes, M; Belle, S H; Krom, R A et al. (1998) Early allograft dysfunction after liver transplantation: a definition and predictors of outcome. National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database. Transplantation 66:302-10
Zetterman, R K; Belle, S H; Hoofnagle, J H et al. (1998) Age and liver transplantation: a report of the Liver Transplantation Database. Transplantation 66:500-6
Wiesner, R H; Demetris, A J; Belle, S H et al. (1998) Acute hepatic allograft rejection: incidence, risk factors, and impact on outcome. Hepatology 28:638-45
Everhart, J E; Lombardero, M; Lake, J R et al. (1998) Weight change and obesity after liver transplantation: incidence and risk factors. Liver Transpl Surg 4:285-96
Everhart, J E; Lombardero, M; Detre, K M et al. (1997) Increased waiting time for liver transplantation results in higher mortality. Transplantation 64:1300-6
Dickson, R C; Everhart, J E; Lake, J R et al. (1997) Transmission of hepatitis B by transplantation of livers from donors positive for antibody to hepatitis B core antigen. The National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database. Gastroenterology 113:1668-74

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