This contract involves the evaluation of the toxic and carcinogenic potential of selected chemicals in laboratory animals. Exposure to these chemicals is via oral administration. The project includes 2-year studies of methacrylonitrile, acrylonitrile, benzophenone, 2-hydroxy-4- methoxybenzophenone, dichlorodiphenylsulfone, dipropylene glycol, and 90- day and 2-year studies of elmiron. Studies for each chemical are divided into phases, with phase 1 efforts including prestart activities including bulk chemical reanalysis, dose formulation and analysis method validation, and biological sample analysis method validation. Acceptable prestart reports must be received before permission is granted to proceed to subsequent phases.

Project Start
1995-08-15
Project End
1999-11-30
Budget Start
2000-03-30
Budget End
2000-09-30
Support Year
Fiscal Year
2000
Total Cost
$250,000
Indirect Cost
Name
Battelle Memorial Institute
Department
Type
DUNS #
City
Columbus
State
OH
Country
United States
Zip Code
43201