Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
3P01AG004207-02S1
Application #
3090783
Study Section
Aging Review Committee (AGE)
Project Start
1984-04-01
Project End
1987-03-31
Budget Start
1985-12-05
Budget End
1986-03-31
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Landfield, P W; Eldridge, J C (1991) The glucocorticoid hypothesis of brain aging and neurodegeneration: recent modifications. Acta Endocrinol (Copenh) 125 Suppl 1:54-64
Kerr, D S; Campbell, L W; Applegate, M D et al. (1991) Chronic stress-induced acceleration of electrophysiologic and morphometric biomarkers of hippocampal aging. J Neurosci 11:1316-24
O'Steen, W K; Brodish, A (1990) Scleral calcification and photoreceptor cell death during aging and exposure to chronic stress. Am J Anat 189:62-8
Odio, M; Brodish, A (1989) Age-related adaptation of pituitary-adrenocortical responses to stress. Neuroendocrinology 49:382-8
Brodish, A; Odio, M (1989) Age-dependent effects of chronic stress on ACTH and corticosterone responses to an acute novel stress. Neuroendocrinology 49:496-501
Odio, M R; Brodish, A (1988) Effects of age on metabolic responses to acute and chronic stress. Am J Physiol 254:E617-24
MacLean, D B; Eldridge, J C; Brodish, A (1988) Substance P and somatostatin content and transport in the vagus and sciatic nerves of the aging Fischer 344 rat. Neurobiol Aging 9:273-7
Sonntag, W E; Goliszek, A G; Brodish, A et al. (1987) Diminished diurnal secretion of adrenocorticotropin (ACTH), but not corticosterone, in old male rats: possible relation to increased adrenal sensitivity to ACTH in vivo. Endocrinology 120:2308-15
Odio, M; Brodish, A; Ricardo Jr, M J (1987) Effects on immune responses by chronic stress are modulated by aging. Brain Behav Immun 1:204-15
O'Steen, W K; Sweatt, A J; Brodish, A (1987) Effects of acute and chronic stress on the neural retina of young, mid-age, and aged Fischer-344 rats. Brain Res 426:37-46

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