Abstract

The Administrative Core will provide overall logistical and financial coordination of the Program Project. The staff of the Administrative Core will organize all of the monthly, quarterly, and annual review meetings and will foster communication between the Executive Committee and all other Investigators in the Program. The Executive Committee, led by the PI and composed of all Project and Core Leaders, will be responsible for the day-to-day handling of the Projects and decisions regarding minor modifications of the Program direction. The Administrative Core will support the salary of the specialized physician to carry out the euglycemic-hyperinsulinemic clamps that are an integral component of Projects 1 and 2, and will support the salary of the subject recruiter who will recruit the human subjects to be studied in Projects 1 and 2. Finally, the Administrative Core will ensure data security, storage, access, and integration among the Projects and Cores, and will assist all Project and Core Leaders in meeting their Data Sharing obligations when the Projects are complete. All Projects and Cores will utilize this Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
2P01AG009975-16A1
Application #
8700633
Study Section
Special Emphasis Panel (ZAG1-ZIJ-2 (M1))
Project Start
2013-08-01
Project End
2018-06-30
Budget Start
2013-08-01
Budget End
2014-06-30
Support Year
16
Fiscal Year
2013
Total Cost
$597,163
Indirect Cost
$240,434

  Institution

Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Leise, Tanya L; Goldberg, Ariella; Michael, John et al. (2018) Recurring circadian disruption alters circadian clock sensitivity to resetting. Eur J Neurosci :
Zitting, Kirsi-Marja; Münch, Mirjam Y; Cain, Sean W et al. (2018) Young adults are more vulnerable to chronic sleep deficiency and recurrent circadian disruption than older adults. Sci Rep 8:11052
McHill, Andrew W; Hull, Joseph T; McMullan, Ciaran J et al. (2018) Chronic Insufficient Sleep Has a Limited Impact on Circadian Rhythmicity of Subjective Hunger and Awakening Fasted Metabolic Hormones. Front Endocrinol (Lausanne) 9:319
Li, Peng; Yu, Lei; Lim, Andrew S P et al. (2018) Fractal regulation and incident Alzheimer's disease in elderly individuals. Alzheimers Dement 14:1114-1125
Todd, William D; Fenselau, Henning; Wang, Joshua L et al. (2018) A hypothalamic circuit for the circadian control of aggression. Nat Neurosci 21:717-724
Naganuma, Fumito; Bandaru, Sathyajit S; Absi, Gianna et al. (2018) Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy. Neurobiol Dis 120:12-20
Asgari-Targhi, Ameneh; Klerman, Elizabeth B (2018) Mathematical modeling of circadian rhythms. Wiley Interdiscip Rev Syst Biol Med :e1439
Kroeger, Daniel; Absi, Gianna; Gagliardi, Celia et al. (2018) Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice. Nat Commun 9:4129
Gottlieb, Daniel J; Ellenbogen, Jeffrey M; Bianchi, Matt T et al. (2018) Sleep deficiency and motor vehicle crash risk in the general population: a prospective cohort study. BMC Med 16:44
Biello, Stephany M; Bonsall, David R; Atkinson, Lynsey A et al. (2018) Alterations in glutamatergic signaling contribute to the decline of circadian photoentrainment in aged mice. Neurobiol Aging 66:75-84

Showing the most recent 10 out of 208 publications