Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
3P01AG010829-02S3
Application #
2052045
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
1993-09-30
Project End
1997-06-30
Budget Start
1994-09-25
Budget End
1995-06-30
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Zhang, X; Azhar, G; Nagano, K et al. (2001) Differential vulnerability to oxidative stress in rat cardiac myocytes versus fibroblasts. J Am Coll Cardiol 38:2055-62
Levy, B R; Hausdorff, J M; Hencke, R et al. (2000) Reducing cardiovascular stress with positive self-stereotypes of aging. J Gerontol B Psychol Sci Soc Sci 55:P205-13
Azhar, G; Liu, L; Zhang, X et al. (1999) Influence of age on hypoxia/reoxygenation-induced DNA fragmentation and bcl-2, bcl-xl, bax and fas in the rat heart and brain. Mech Ageing Dev 112:5-25
Azhar, G; Gao, W; Liu, L et al. (1999) Ischemia-reperfusion in the adult mouse heart influence of age. Exp Gerontol 34:699-714
Spindler, M; Saupe, K W; Tian, R et al. (1999) Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A(31)P NMR magnetization transfer study of the intact beating rat heart. J Mol Cell Cardiol 31:2175-89
Vijg, J (1999) Genetics of aging. Sponsored by Cold Spring Harbor Laboratory, 2-5 April 1998. Biochim Biophys Acta 1423:R1-12
Khrapko, K; Bodyak, N; Thilly, W G et al. (1999) Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions. Nucleic Acids Res 27:2434-41
van Orsouw, N J; Zhang, X; Wei, J Y et al. (1998) Mutational scanning of mitochondrial DNA by two-dimensional electrophoresis. Genomics 52:27-36
Liu, L; Azhar, G; Gao, W et al. (1998) Bcl-2 and Bax expression in adult rat hearts after coronary occlusion: age-associated differences. Am J Physiol 275:R315-22
Turner, N A; Xia, F; Azhar, G et al. (1998) Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells. J Mol Cell Cardiol 30:1789-801

Showing the most recent 10 out of 23 publications