Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
2P01AG012992-06
Application #
6356222
Study Section
Project Start
2000-09-30
Project End
2001-08-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Zhang, Ke; Donnelly, Christopher J; Haeusler, Aaron R et al. (2015) The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature 525:56-61
Matthews, Christopher C; Fishman, Paul S; Wittenberg, George F (2014) Tetanus toxin reduces local and descending regulation of the H-reflex. Muscle Nerve 49:495-501
van Zundert, Brigitte; Peuscher, Marieke H; Hynynen, Meri et al. (2008) Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis. J Neurosci 28:10864-74
Ranganathan, Srikanth; Williams, Eric; Ganchev, Philip et al. (2005) Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis. J Neurochem 95:1461-71
Ryu, Hoon; Smith, Karen; Camelo, Sandra I et al. (2005) Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice. J Neurochem 93:1087-98
Maxwell, Michele M; Pasinelli, Piera; Kazantsev, Aleksey G et al. (2004) RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells. Proc Natl Acad Sci U S A 101:3178-83
Ulug, Aziz M; Grunewald, Thomas; Lin, Michael T et al. (2004) Diffusion tensor imaging in the diagnosis of primary lateral sclerosis. J Magn Reson Imaging 19:34-9
Klivenyi, Peter; Kiaei, Mahmoud; Gardian, Gabrielle et al. (2004) Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem 88:576-82
Pasinelli, Piera; Belford, Mary Elizabeth; Lennon, Niall et al. (2004) Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria. Neuron 43:19-30
Klivenyi, Peter; Calingasan, Noel Y; Starkov, Anatoly et al. (2004) Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase. Neurobiol Dis 15:610-7

Showing the most recent 10 out of 89 publications