The main functions of the Administrative Core are to: a) facilitate distribution of research materials andresources to the various investigators; b) facilitate communication between investigators, cores the advisorycommittees, affiliated institutions and the funding agency; c) evaluate the quality of ongoing research as wellas programs to be considered for future expansion; d) cut brain tissue specimens and harvest frozenspecimens for distribution, in a blinded fashion for investigators; d) maintain a web page for the PPG. Corefunctions will be accomplished with the help of three different committees: 1) the Internal Advisory groupconsisting of leaders, co-leaders, and co-investigators of all cores and research projects. It will meet on amonthly basis to discuss research projects, protocols, results and any problems that might arise in thecollaborative effort. The external Advisory Committee which consists of scientists with expertise in variousdisciplines represented in this application will meet with Internal Advisory Committee every other a year. Itwill review progress and advise on the overall quality of the work. Members of the Chicago Alzheimer'sDisease Research Network will meet twice a year with investigators from the Program Project. Thesemeetings will provide a forum for discussing new ideas and a mechanism for expanding the program withworthy projects in the future. The Administrative Core will be led by the Principal Investigator and Co-PL ofthe Core
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