Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG014669-01A1
Application #
2777875
Study Section
Project Start
Project End
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Type
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Szabo, Paul; Shen, Steven; Telford, William et al. (2003) Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice. Cell Immunol 222:78-87
Posnett, David N; Yarilin, Dmitry; Valiando, Jennifer R et al. (2003) Oligoclonal expansions of antigen-specific CD8+ T cells in aged mice. Ann N Y Acad Sci 987:274-9
Weksler, Marc E; Goodhardt, Michele; Szabo, Paul (2002) The effect of age on B cell development and humoral immunity. Springer Semin Immunopathol 24:35-52
Weksler, Marc E; Relkin, Norman; Turkenich, Rimma et al. (2002) Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals. Exp Gerontol 37:943-8
Komers, R; Anderson, S; Epstein, M (2001) Renal and cardiovascular effects of selective cyclooxygenase-2 inhibitors. Am J Kidney Dis 38:1145-57
Radu, D L; Weksler, M E; Bona, C A (2001) Maintenance of size and function of influenza virus hemagglutinin specific transgenic T-cell clone during life. J Cell Mol Med 5:388-96
Li, F; Jin, F; Freitas, A et al. (2001) Impaired regeneration of the peripheral B cell repertoire from bone marrow following lymphopenia in old mice. Eur J Immunol 31:500-5
Weksler, M E (2000) Changes in the B-cell repertoire with age. Vaccine 18:1624-8
Weksler, M E; Szabo, P (2000) The effect of age on the B-cell repertoire. J Clin Immunol 20:240-9
LeMaoult, J; Messaoudi, I; Manavalan, J S et al. (2000) Age-related dysregulation in CD8 T cell homeostasis: kinetics of a diversity loss. J Immunol 165:2367-73

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