Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
2P01AG017242-06
Application #
6764783
Study Section
Special Emphasis Panel (ZAG1-ZIJ-5 (J3))
Program Officer
Mccormick, Anna M
Project Start
1999-04-01
Project End
2009-03-31
Budget Start
2004-09-01
Budget End
2005-03-31
Support Year
6
Fiscal Year
2004
Total Cost
$1,321,484
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Physiology
Type
Other Domestic Higher Education
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Lau, Cia-Hin; Suh, Yousin (2018) In vivo epigenome editing and transcriptional modulation using CRISPR technology. Transgenic Res 27:489-509
Wiley, Christopher D; Schaum, Nicholas; Alimirah, Fatouma et al. (2018) Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype. Sci Rep 8:2410
Quispe-Tintaya, Wilber; Lee, Moonsook; Dong, Xiao et al. (2018) Bleomycin-induced genome structural variations in normal, non-tumor cells. Sci Rep 8:16523
Hébert, Jean M; Vijg, Jan (2018) Cell Replacement to Reverse Brain Aging: Challenges, Pitfalls, and Opportunities. Trends Neurosci 41:267-279
Wiley, Christopher D; Flynn, James M; Morrissey, Christapher et al. (2017) Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence. Aging Cell 16:1043-1050
Milholland, Brandon; Dong, Xiao; Zhang, Lei et al. (2017) Differences between germline and somatic mutation rates in humans and mice. Nat Commun 8:15183
Baar, Marjolein P; Brandt, Renata M C; Putavet, Diana A et al. (2017) Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell 169:132-147.e16
Milholland, Brandon; Suh, Yousin; Vijg, Jan (2017) Mutation and catastrophe in the aging genome. Exp Gerontol 94:34-40
La Fata, G; van Vliet, N; Barnhoorn, S et al. (2017) Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model. J Prev Alzheimers Dis 4:226-235
Zhu, Yizhou; Tazearslan, Cagdas; Suh, Yousin (2017) Challenges and progress in interpretation of non-coding genetic variants associated with human disease. Exp Biol Med (Maywood) 242:1325-1334

Showing the most recent 10 out of 253 publications