Abstract

ADMINISTRATIVE COREA.
SPECIFIC AIMS The overall goal of the Administrative Core of this Program Project Grant (PPG) is to facilitate the progressof the research program, to oversee budgetary and administrative problems, to disseminate information,and to foster interactions among researchers in different projects.
SPECIFIC AIM 1 : COORDINATE AND OVERSEE THE ADMINISTRATIVE ACTIVITIES OF THE PPGSPECIFIC AIM 2: FOSTER INTERACTIONS AMONG RESEARCHERS IN THE PPGSPECIFIC AIM 3: ORGANIZE A SEMINAR SERIES TO FOCUS ON AD AND RELATED SUBJECTSSPECIFIC AIM 4: PROVIDE STATISTICAL ANALYSESSPECIFIC AIM 5: PROVIDE EMERGENCY FUNDS FOR THE REPAIR OR REPLACEMENT OF EQUIPMENTSPECIFIC AIM 6: DESIGN A WEBSITE FOR THE PPGSPECIFIC AIM 7: ESTABLISH THE ADVISORY COMMITTEESPECIFIC AIM 8: ORGANIZE NATIONAL AND INTERNATIONAL SYMPOSIA AND MEETINGS

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
2P01AG018357-06A1
Application #
7192127
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4 (O3))
Project Start
2007-05-01
Project End
2012-04-30
Budget Start
2007-05-01
Budget End
2008-04-30
Support Year
6
Fiscal Year
2007
Total Cost
$63,161
Indirect Cost

  Institution

Name
University of Missouri-Columbia
Department
Type
DUNS #
153890272
City
Columbia
State
MO
Country
United States
Zip Code
65211

  Publications

Simonyi, Agnes; Chen, Zihong; Jiang, Jinghua et al. (2015) Inhibition of microglial activation by elderberry extracts and its phenolic components. Life Sci 128:30-8
Erb, Laurie; Cao, Chen; Ajit, Deepa et al. (2015) P2Y receptors in Alzheimer's disease. Biol Cell 107:1-21
Yang, X; Sheng, W; Ridgley, D M et al. (2015) Astrocytes regulate ?-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2. Neuroscience 300:508-17
Walker, Jennifer M; Klakotskaia, Diana; Ajit, Deepa et al. (2015) Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model. J Alzheimers Dis 44:561-72
Sun, Grace Y; Chuang, Dennis Y; Zong, Yijia et al. (2014) Role of cytosolic phospholipase A2 in oxidative and inflammatory signaling pathways in different cell types in the central nervous system. Mol Neurobiol 50:6-14
Afshordel, Sarah; Wood, Wellington Gibson; Igbavboa, Urule et al. (2014) Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain. J Neurochem 129:732-42
Liao, Zhongji; Cao, Chen; Wang, Jianjie et al. (2014) The P2Y2 Receptor Interacts with VE-Cadherin and VEGF Receptor-2 to Regulate Rac1 Activity in Endothelial Cells. J Biomed Sci Eng 7:1105-1121
Ajit, Deepa; Woods, Lucas T; Camden, Jean M et al. (2014) Loss of P2Y? nucleotide receptors enhances early pathology in the TgCRND8 mouse model of Alzheimer's disease. Mol Neurobiol 49:1031-42
Wood, W Gibson; Li, Ling; Müller, Walter E et al. (2014) Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis. J Neurochem 129:559-72
Wood, W Gibson; Igbavboa, Urule; Muller, Walter E et al. (2013) Statins, Bcl-2, and apoptosis: cell death or cell protection? Mol Neurobiol 48:308-14

Showing the most recent 10 out of 113 publications