Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
3P01AG020752-01S1
Application #
6550438
Study Section
Special Emphasis Panel (ZAG1)
Project Start
2001-09-15
Project End
2002-07-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Jin, Jingling; Iakova, Polina; Jiang, Yanjun et al. (2011) The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation. Hepatology 54:989-98
Iakova, Polina; Timchenko, Lubov; Timchenko, Nikolai A (2011) Intracellular signaling and hepatocellular carcinoma. Semin Cancer Biol 21:28-34
Singh, Pallavi; Goode, Triona; Dean, Adam et al. (2011) Elevated interferon gamma signaling contributes to impaired regeneration in the aged liver. J Gerontol A Biol Sci Med Sci 66:944-56
Hornsby, Peter J (2011) Cellular aging and cancer. Crit Rev Oncol Hematol 79:189-95
Yuan, Furong; Chen, Meizhen; Hornsby, Peter J (2010) Fibroblasts from Werner syndrome patients: cancer cells derived by experimental introduction of oncogenes maintain malignant properties despite entering crisis. Oncol Rep 23:377-86
Jin, Jingling; Wang, Guo-Li; Iakova, Polina et al. (2010) Epigenetic changes play critical role in age-associated dysfunctions of the liver. Aging Cell 9:895-910
Wang, Guo-Li; Shi, Xiurong; Haefliger, Simon et al. (2010) Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice. J Clin Invest 120:2549-62
Lin, Qiushi; Chen, Dahu; Timchenko, Nikolai A et al. (2010) SKI promotes Smad3 linker phosphorylations associated with the tumor-promoting trait of TGFbeta. Cell Cycle 9:1684-9
Cardoso, Cibele C; Bornstein, Stefan R; Hornsby, Peter J (2010) Optimizing orthotopic cell transplantation in the mouse adrenal gland. Cell Transplant 19:565-72
Willis-Martinez, Danielle; Richards, Hunter W; Timchenko, Nikolai A et al. (2010) Role of HDAC1 in senescence, aging, and cancer. Exp Gerontol 45:279-85

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