Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG021654-05
Application #
7499395
Study Section
Special Emphasis Panel (ZAG1-ZIJ-2 (O4))
Project Start
2007-08-01
Project End
2008-06-30
Budget Start
2007-08-01
Budget End
2008-06-30
Support Year
5
Fiscal Year
2007
Total Cost
$207,010
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Type
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Sathyan, Sanish; Barzilai, Nir; Atzmon, Gil et al. (2018) Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. Front Med (Lausanne) 5:105
Mao, Kai; Quipildor, Gabriela Farias; Tabrizian, Tahmineh et al. (2018) Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. Nat Commun 9:2394
Hui, Ken Y; Fernandez-Hernandez, Heriberto; Hu, Jianzhong et al. (2018) Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Sci Transl Med 10:
Gubbi, Sriram; Quipildor, Gabriela Farias; Barzilai, Nir et al. (2018) 40 YEARS of IGF1: IGF1: the Jekyll and Hyde of the aging brain. J Mol Endocrinol 61:T171-T185
Ben-Avraham, Danny; Govindaraju, Diddahally R; Budagov, Temuri et al. (2017) The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. Sci Adv 3:e1602025
Sathyan, Sanish; Barzilai, Nir; Atzmon, Gil et al. (2017) Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population. Neurobiol Aging 58:238.e1-238.e8
Milman, Sofiya; Huffman, Derek M; Barzilai, Nir (2016) The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research. Cell Metab 23:980-989
Barzilai, Nir; Crandall, Jill P; Kritchevsky, Stephen B et al. (2016) Metformin as a Tool to Target Aging. Cell Metab 23:1060-1065
Huffman, Derek M; Farias Quipildor, Gabriela; Mao, Kai et al. (2016) Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline. Aging Cell 15:181-6
Ismail, Khadija; Nussbaum, Lisa; Sebastiani, Paola et al. (2016) Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity. J Am Geriatr Soc 64:1583-91

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