Aging is characterized by a paradox between mild to serious health-related deterioration including cognitive decline and neurodegenerative disorders and improved socioemotional functioning and well-being. This latter finding is characterized by subjective reports of increased general life satisfaction and psychological well-being in the elderly, decline in reported negative mood states, particularly among women, as good or improved positive moods compared to young adults and greater involvement in close social relationships, especially among females and kin. One of the primary theories put forth over the last few decades to explain this apparent paradox is the Socioemotional Selectivity Theory (SST). According to this theory, reported emotional satisfaction among the aged is not simply due to lower expectations for social relationships or day- to-day mood quality, but to an active and selective management of social relationships and activities to maximize positive emotional interactions and minimize negative experiences. This project will use the SST to guide studies of age-related changes in social cognition among three species of female primates. This project will address 3 Specific Aims. First, we will examine age and species differences in processing familiar vs. unfamiliar conspecific's faces and facial expressions. Second, we will examine age and species differences in the relationship between emotion and attention using reaction time measures in an emotional priming task. Finally, we will use both longitudinal and cross-sectional archival data from nonhuman primates to address whether the quality of social relationships changes with aging such that older females selectively associate with close friends and relatives compared to novel or less familiar individuals. Such a broad comparative study focusing on females will provide important insights into the unique aspects of human aging, the brain mechanisms that are most affected by age-related changes in cognition and emotion, and provide a means for understanding the impact these changes may have on the social organization of related species, which is largely influenced by females.
| Xu, Ting; Falchier, Arnaud; Sullivan, Elinor L et al. (2018) Delineating the Macroscale Areal Organization of the Macaque Cortex In Vivo. Cell Rep 23:429-441 |
| Martin, Allison L; Franklin, Andrea N; Perlman, Jaine E et al. (2018) Systematic assessment of food item preference and reinforcer effectiveness: Enhancements in training laboratory-housed rhesus macaques. Behav Processes 157:445-452 |
| Donahue, Chad J; Glasser, Matthew F; Preuss, Todd M et al. (2018) Quantitative assessment of prefrontal cortex in humans relative to nonhuman primates. Proc Natl Acad Sci U S A 115:E5183-E5192 |
| Mars, Rogier B; Sotiropoulos, Stamatios N; Passingham, Richard E et al. (2018) Whole brain comparative anatomy using connectivity blueprints. Elife 7: |
| Lacreuse, Agnès; Parr, Lisa; Chennareddi, Lakshmi et al. (2018) Age-related decline in cognitive flexibility in female chimpanzees. Neurobiol Aging 72:83-88 |
| Bruner, Emiliano; Preuss, Todd M; Chen, Xu et al. (2017) Evidence for expansion of the precuneus in human evolution. Brain Struct Funct 222:1053-1060 |
| Pereira-Pedro, Ana Sofia; Rilling, James K; Chen, Xu et al. (2017) Midsagittal Brain Variation among Non-Human Primates: Insights into Evolutionary Expansion of the Human Precuneus. Brain Behav Evol 90:255-263 |
| Hecht, E E; Mahovetz, L M; Preuss, T M et al. (2017) A neuroanatomical predictor of mirror self-recognition in chimpanzees. Soc Cogn Affect Neurosci 12:37-48 |
| Donahue, Chad J; Sotiropoulos, Stamatios N; Jbabdi, Saad et al. (2016) Using Diffusion Tractography to Predict Cortical Connection Strength and Distance: A Quantitative Comparison with Tracers in the Monkey. J Neurosci 36:6758-70 |
| Rosen, Rebecca F; Tomidokoro, Yasushi; Farberg, Aaron S et al. (2016) Comparative pathobiology of ?-amyloid and the unique susceptibility of humans to Alzheimer's disease. Neurobiol Aging 44:185-196 |
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