Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Messina, J P; Gilkeson, G S; Pisetsky, D S (1993) The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens. Cell Immunol 147:148-57
Weinberg, J B; Wortham, T S; Misukonis, M A et al. (1993) Synovial mononuclear phagocytes in rheumatoid arthritis and osteoarthritis: quantitative and functional aspects. Immunol Invest 22:365-74
Robertson, C R; Gilkeson, G S; Ward, M M et al. (1992) Patterns of heavy and light chain utilization in the antibody response to single-stranded bacterial DNA in normal human subjects and patients with systemic lupus erythematosus. Clin Immunol Immunopathol 62:25-32
Hale, L P; Haynes, B F (1992) Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation. J Immunol 149:3809-16
Pincus, S H; Cole, R; Pisetsky, D S (1992) A defect in the humoral immune response to protein antigens and haptens in immunoglobulin mu heavy-chain transgenic mice. Mol Immunol 29:801-6
Pisetsky, D S (1992) Anti-DNA antibodies in systemic lupus erythematosus. Rheum Dis Clin North Am 18:437-54
Wu, S; Rodabaugh, K; Martinez-Maza, O et al. (1992) Stimulation of ovarian tumor cell proliferation with monocyte products including interleukin-1, interleukin-6, and tumor necrosis factor-alpha. Am J Obstet Gynecol 166:997-1007
Gilkeson, G S; Spurney, R; Coffman, T M et al. (1992) Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice. Clin Immunol Immunopathol 64:166-72
Robertson, C R; Pisetsky, D S (1992) Specificity analysis of antibodies to single-stranded micrococcal DNA in the sera of normal human subjects and patients with systemic lupus erythematosus. Clin Exp Rheumatol 10:589-94
Weinberg, J B; Pippen, A M; Greenberg, C S (1991) Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum 34:996-1005

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