Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
2P01AI037232-05
Application #
6231059
Study Section
Special Emphasis Panel (ZAI1-SCO-M (J1))
Project Start
1999-09-22
Project End
2004-08-31
Budget Start
Budget End
Support Year
5
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Veterans Medical Research Fdn/San Diego
Department
Type
DUNS #
933863508
City
San Diego
State
CA
Country
United States
Zip Code
92161
Hung, Chiung-Yu; Xue, Jianmin; Cole, Garry T (2007) Virulence mechanisms of coccidioides. Ann N Y Acad Sci 1111:225-35
Nosanchuk, Joshua D; Yu, Jieh-Juen; Hung, Chiung-Yu et al. (2007) Coccidioides posadasii produces melanin in vitro and during infection. Fungal Genet Biol 44:517-20
Shubitz, Lisa F; Yu, Jieh-Juen; Hung, Chiung-Yu et al. (2006) Improved protection of mice against lethal respiratory infection with Coccidioides posadasii using two recombinant antigens expressed as a single protein. Vaccine 24:5904-11
Mirbod-Donovan, Fariba; Schaller, Ruth; Hung, Chiung-Yu et al. (2006) Urease produced by Coccidioides posadasii contributes to the virulence of this respiratory pathogen. Infect Immun 74:504-15
Xue, Jianmin; Hung, Chiung-Yu; Yu, Jieh-Juen et al. (2005) Immune response of vaccinated and non-vaccinated mice to Coccidioides posadasii infection. Vaccine 23:3535-44
Hung, Chiung-Yu; Seshan, Kalpathi R; Yu, Jieh-Juen et al. (2005) A metalloproteinase of Coccidioides posadasii contributes to evasion of host detection. Infect Immun 73:6689-703
Johannesson, Hanna; Townsend, Jeffrey P; Hung, Chiung-Yu et al. (2005) Concerted evolution in the repeats of an immunomodulating cell surface protein, SOWgp, of the human pathogenic fungi Coccidioides immitis and C. posadasii. Genetics 171:109-17
Cole, G T; Xue, J M; Okeke, C N et al. (2004) A vaccine against coccidioidomycosis is justified and attainable. Med Mycol 42:189-216
Johannesson, Hanna; Vidal, Pilar; Guarro, Josep et al. (2004) Positive directional selection in the proline-rich antigen (PRA) gene among the human pathogenic fungi Coccidioides immitis, C. posadasii and their closest relatives. Mol Biol Evol 21:1134-45
Delgado, Nelson; Xue, Jianmin; Yu, Jieh-Juen et al. (2003) A recombinant beta-1,3-glucanosyltransferase homolog of Coccidioides posadasii protects mice against coccidioidomycosis. Infect Immun 71:3010-9

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