Abstract

The function of Core this (Non-human Primate Core) will be to carry out all macaque experiments as described in Projects 1 - 3. The Core will purchase, house, vaccinate, challenge, and monitor all macaques studied in this HIV-RAD Program. Samples from individual experiments will be prepared, aliquoted, and stored or shipped under direction from the Administrative Core. All samples will be available to each HIV-RAD Project for analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI046023-04
Application #
6655158
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2002-09-01
Project End
2003-07-31
Budget Start
Budget End
Support Year
4
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Verma, Shefali S; Frase, Alex T; Verma, Anurag et al. (2016) PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG). Pac Symp Biocomput 21:57-68
Fluet, M E; Whitmore, A C; Moshkoff, D A et al. (2008) Effects of rapid antigen degradation and VEE glycoprotein specificity on immune responses induced by a VEE replicon vaccine. Virology 370:22-32
Thompson, Joseph M; Nicholson, Michael G; Whitmore, Alan C et al. (2008) Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. J Immunol 181:574-85
Thompson, Joseph M; Whitmore, Alan C; Staats, Herman F et al. (2008) The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines. Vaccine 26:4998-5003
Thompson, Joseph M; Whitmore, Alan C; Staats, Herman F et al. (2008) Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen. Vaccine 26:4267-75
Tang, Y; Swanstrom, R (2008) Development and characterization of a new single cycle vaccine vector in the simian immunodeficiency virus model system. Virology 372:72-84
Cecil, Chad; West, Ande; Collier, Martha et al. (2007) Structure and immunogenicity of alternative forms of the simian immunodeficiency virus gag protein expressed using Venezuelan equine encephalitis virus replicon particles. Virology 362:362-73
Liao, Hua-Xin; Sutherland, Laura L; Xia, Shi-Mao et al. (2006) A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. Virology 353:268-82
Thompson, Joseph M; Whitmore, Alan C; Konopka, Jennifer L et al. (2006) Mucosal and systemic adjuvant activity of alphavirus replicon particles. Proc Natl Acad Sci U S A 103:3722-7
Johnston, Robert E; Johnson, Philip R; Connell, Mary J et al. (2005) Vaccination of macaques with SIV immunogens delivered by Venezuelan equine encephalitis virus replicon particle vectors followed by a mucosal challenge with SIVsmE660. Vaccine 23:4969-79

Showing the most recent 10 out of 11 publications