Abstract

The Rockefeller University, through the Starr Center for Human Genetics, has created a Core facility for high throughput genotyping. This facility will be utilized by the Program Project group to develop mouse microsatellite mapping for the generation of speed congenics between the various transgenic and knockout strains generated by the Program Project. Since the infrastructure and instrumentation, described below, is already in place, the Program Project will contribute reagent costs ($0.25/genotype) and a full-time technician for DNA preparation, data assembly and overall responsibility for working with the Genotyping Core facility. Dr. Jeffrey Ravetch, the Program Project Director, will be responsible for overseeing the interactions of the Program Project team and the Genotyping Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
1P01AI051573-01
Application #
6493841
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2002-04-01
Project End
2007-03-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

Sela, Uri; Park, Chae Gyu; Park, Andrew et al. (2016) Dendritic Cells Induce a Subpopulation of IL-12R?2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses. PLoS One 11:e0146412
Guermonprez, Pierre; Helft, Julie; Claser, Carla et al. (2013) Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nat Med 19:730-8
Schreiber, Heidi A; Loschko, Jakob; Karssemeijer, Roos A et al. (2013) Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium. J Exp Med 210:2025-39
Bozzacco, Leonia; Yu, Haiqiang (2013) Identification and quantitation of MHC class II-bound peptides from mouse spleen dendritic cells by immunoprecipitation and mass spectrometry analysis. Methods Mol Biol 1061:231-43
Bozzacco, Leonia; Yu, Haiqiang; Dengjel, Jorn et al. (2012) Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein. PLoS One 7:e41897
Meredith, Matthew M; Liu, Kang; Kamphorst, Alice O et al. (2012) Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. J Exp Med 209:1583-93
Meredith, Matthew M; Liu, Kang; Darrasse-Jeze, Guillaume et al. (2012) Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. J Exp Med 209:1153-65
Wang, Bei; Zaidi, Neeha; He, Li-Zhen et al. (2012) Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice. Breast Cancer Res 14:R39
Bozzacco, Leonia; Yu, Haiqiang; Zebroski, Henry A et al. (2011) Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells. J Proteome Res 10:5016-30
Li, Fubin; Ravetch, Jeffrey V (2011) Inhibitory Fc? receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies. Science 333:1030-4

Showing the most recent 10 out of 40 publications