This P01 proposal will depend upon rapid access to both information (to be supplied and utilized by all threeof the groups) and materials: especially genetically modified organisms, to be transferred between Osakaand La Jolla. The P01 will also yield information and organisms for use by the entire scientific community.The Administrative Core will oversee and facilitate these transfers: both within the Program and to the restof the scientific community. It will assure compliance with institutional, national, and international regulationsgoverning material transfer, animal use,and disbursement of funds. It will also coordinate direct interactionsbetween the participating investigators, by means of teleconference, and by means of annual meetings. TheAdministrative Core will also oversee and edit a web site, to permit immediate access to data needed withinthe Program as a whole and by the scientific community at large.
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