The Administrative Core consists of two major functional units - the Executive Unit and the Data Management, Statistics, and Information Technology (DMS/IT) Unit.
The Aims of the Executive Unit are to 1) provide overall scientific and programmatic leadership and direction, 2) oversee and coordinate the activities of Projects 1 and 2, 3) ensure reliable exchange of information and collaboration among all the units and investigators, 4) coordinate and oversee management of the Program Project's fiscal resources, and 5) promote and ensure the Program Project's adherence to relevant federal, University, and IRB requirements.
The Aims of the Data Management, Statistics, and Information Technology (DMS/IT) Unit are to 6) provide a state-of-the-art data management system and methods capable of supporting the interactive projects of multiple participating investigators, 7) provide a set of online resources and communications technologies that facilitate scholarly exchange, distance-independent collaboration, information dissemination and project-specific training, and 8) provide statistical expertise in design, modeling, data analysis, statistical writing, and the development of novel methodologies as related to the execution of Projects 1 and 2. Related to the specific aims of Project 1 and 2, the Clinical and Specimen Core will recruit a substantial number of study participants, each of whom will contribute clinical specimens for laboratory evaluation. Project 1 will generate epidemiological and behavioral data on the participants, while Project 2 will generate laboratory data using the clinical specimens. The Administrative Core will play a central role in coordinating the administrative, fiscal and personnel support required to achieve the scientific mission of these components and fostering the synergistic interaction among them. The Administrative Core will also be critical in managing the extensive amount of data from these projects and conducting the sophisticated analyses necessary to provide robust and valid conclusions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI074621-03
Application #
8035457
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-03-01
Budget End
2011-02-28
Support Year
3
Fiscal Year
2010
Total Cost
$972,384
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Chaillon, Antoine; Gianella, Sara; Lada, Steven M et al. (2018) Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol 92:
Morris, Sheldon R; Zhao, Mitchell; Smith, Davey M et al. (2017) Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis 64:428-434
Osorio, Georgina; Hoenigl, Martin; Quartarolo, Jennifer et al. (2017) Evaluation of opt-out inpatient HIV screening at an urban teaching hospital. AIDS Care 29:1014-1018
Pines, Heather A; Karris, Maile Y; Little, Susan J (2017) Sexual Partner Concurrency Among Partners Reported by MSM with Recent HIV Infection. AIDS Behav 21:3026-3034
Gianella, Sara; Chaillon, Antoine; Mutlu, Ece A et al. (2017) Effect of cytomegalovirus and Epstein-Barr virus replication on intestinal mucosal gene expression and microbiome composition of HIV-infected and uninfected individuals. AIDS 31:2059-2067
Hoenigl, Martin; Braun, Dominique L; Kouyos, Roger et al. (2017) Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection. J Acquir Immune Defic Syndr 74:e114-e117
Graves, Susannah K; Little, Susan J; Hoenigl, Martin (2017) Risk profile and HIV testing outcomes of women undergoing community-based testing in San Diego 2008-2014. Sci Rep 7:42183
Green, Nella; Hoenigl, Martin; Chaillon, Antoine et al. (2017) Partner services in adults with acute and early HIV infection. AIDS 31:287-293
Gianella, Sara; Taylor, Jeff; Brown, Timothy R et al. (2017) Can research at the end of life be a useful tool to advance HIV cure? AIDS 31:1-4
Vesa, Jouni; Chaillon, Antoine; Wagner, Gabriel A et al. (2017) Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles. AIDS 31:1149-1158

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