This Program Project involves the participation of researchers from 5 different Institutions each of them located in a distinct city and state (University of Texas Medical Branch in Galveston, TX;University of Kentucky in Lexington, KY;National Animal Disease Center in Ames, IO, Hematech Inc in Sioux Falls, SD; and Case Western Reserve University in Cleveland, OH). To reach the aims of this project it is essential to maintain an effective integration and communication of the different participants in this initiative. The main goal of the Administrative Core is to integrate Projects and Cores and take care of all administrative aspects needed for the smooth operation of the Program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI077774-03
Application #
8129597
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-08-01
Budget End
2011-07-31
Support Year
3
Fiscal Year
2010
Total Cost
$116,199
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Type
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
Moreno, Julie A; Telling, Glenn C (2018) Molecular Mechanisms of Chronic Wasting Disease Prion Propagation. Cold Spring Harb Perspect Med 8:
Davenport, Kristen A; Mosher, Brittany A; Brost, Brian M et al. (2018) Assessment of Chronic Wasting Disease Prion Shedding in Deer Saliva with Occupancy Modeling. J Clin Microbiol 56:
Haley, Nicholas J; Henderson, Davin M; Wycoff, Sarah et al. (2018) Chronic wasting disease management in ranched elk using rectal biopsy testing. Prion 12:93-108
Haley, Nicholas J; Richt, Jürgen A; Davenport, Kristen A et al. (2018) Design, implementation, and interpretation of amplification studies for prion detection. Prion 12:73-82
Yuan, Qi; Telling, Glenn; Bartelt-Hunt, Shannon L et al. (2018) Dehydration of Prions on Environmentally Relevant Surfaces Protects Them from Inactivation by Freezing and Thawing. J Virol 92:
Pritzkow, Sandra; Morales, Rodrigo; Lyon, Adam et al. (2018) Efficient prion disease transmission through common environmental materials. J Biol Chem 293:3363-3373
Moreno, Julie A; Telling, Glenn C (2017) Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases. Methods Mol Biol 1658:219-252
Hoover, Clare E; Davenport, Kristen A; Henderson, Davin M et al. (2017) Pathways of Prion Spread during Early Chronic Wasting Disease in Deer. J Virol 91:
Bian, Jifeng; Khaychuk, Vadim; Angers, Rachel C et al. (2017) Prion replication without host adaptation during interspecies transmissions. Proc Natl Acad Sci U S A 114:1141-1146
Henderson, Davin M; Tennant, Joanne M; Haley, Nicholas J et al. (2017) Detection of chronic wasting disease prion seeding activity in deer and elk feces by real-time quaking-induced conversion. J Gen Virol 98:1953-1962

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