Abstract

? Core C The TBSGC is a large, multi-institutional program with several different investigators and collaborators. The goal of Core C is to provide administrative support and program management across the varying projects and sites.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
2P01AI095208-05A1
Application #
9491526
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2018-04-01
Budget End
2019-03-31
Support Year
5
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
Texas A&M Agrilife Research
Department
Type
DUNS #
847205713
City
College Station
State
TX
Country
United States
Zip Code
77843

  Publications

Rittershaus, Emily S C; Baek, Seung-Hun; Krieger, Inna V et al. (2018) A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. Cell Chem Biol 25:1495-1505.e3
Tuukkanen, Anne T; Freire, Diana; Chan, Sum et al. (2018) Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems. J Mol Biol :
Pham, Truc V; Murkin, Andrew S; Moynihan, Margaret M et al. (2017) Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A 114:7617-7622
Cheng, Yu-Shan; Sacchettini, James C (2016) Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance. Biochemistry 55:1107-19
Bajaj, R Alexandra; Arbing, Mark A; Shin, Annie et al. (2016) Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response. Acta Crystallogr F Struct Biol Commun 72:863-869
Wagner, Jonathan M; Chan, Sum; Evans, Timothy J et al. (2016) Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. BMC Struct Biol 16:5
Huang, Hsiao-Ling; Krieger, Inna V; Parai, Maloy K et al. (2016) Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. J Biol Chem 291:27421-27432
Costa, Diego L; Namasivayam, Sivaranjani; Amaral, Eduardo P et al. (2016) Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes. MBio 7:
Matsui, Toshitaka; Nambu, Shusuke; Goulding, Celia W et al. (2016) Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation. Proc Natl Acad Sci U S A 113:3779-84
Olive, Andrew J; Sassetti, Christopher M (2016) Metabolic crosstalk between host and pathogen: sensing, adapting and competing. Nat Rev Microbiol 14:221-34

Showing the most recent 10 out of 44 publications