Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Program Projects (P01)
Project #
5P01AR020553-14
Application #
3092339
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1978-05-01
Project End
1993-04-30
Budget Start
1990-05-01
Budget End
1991-04-30
Support Year
14
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University City Science Center
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Myers, Jeanne C; Amenta, Peter S; Dion, Arnold S et al. (2007) The molecular structure of human tissue type XV presents a unique conformation among the collagens. Biochem J 404:535-44
Shahan, Tracy; Grant, Derrick; Tootell, Mason et al. (2004) Oncothanin, a peptide from the alpha3 chain of type IV collagen, modifies endothelial cell function and inhibits angiogenesis. Connect Tissue Res 45:151-63
Myers, Jeanne C; Li, Deqin; Amenta, Peter S et al. (2003) Type XIX collagen purified from human umbilical cord is characterized by multiple sharp kinks delineating collagenous subdomains and by intermolecular aggregates via globular, disulfide-linked, and heparin-binding amino termini. J Biol Chem 278:32047-57
Fawzi, A; Robinet, A; Monboisse, J C et al. (2000) A peptide of the alpha 3(IV) chain of type IV collagen modulates stimulated neutrophil function via activation of cAMP-dependent protein kinase and Ser/Thr protein phosphatase. Cell Signal 12:327-35
Shahan, T A; Fawzi, A; Bellon, G et al. (2000) Regulation of tumor cell chemotaxis by type IV collagen is mediated by a Ca(2+)-dependent mechanism requiring CD47 and the integrin alpha(V)beta(3). J Biol Chem 275:4796-802
Pasco, S; Han, J; Gillery, P et al. (2000) A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells. Cancer Res 60:467-73
Shahan, T A; Ohno, N; Pasco, S et al. (1999) Inhibition of tumor cell proliferation by type IV collagen requires increased levels of cAMP. Connect Tissue Res 40:221-32
Shahan, T A; Ziaie, Z; Pasco, S et al. (1999) Identification of CD47/integrin-associated protein and alpha(v)beta3 as two receptors for the alpha3(IV) chain of type IV collagen on tumor cells. Cancer Res 59:4584-90
Han, J; Jenq, W; Kefalides, N A (1999) Integrin alpha2beta1 recognizes laminin-2 and induces C-erb B2 tyrosine phosphorylation in metastatic human melanoma cells. Connect Tissue Res 40:283-93
Zhang, Y; Niu, Z; Cohen, A J et al. (1999) The internal chondrocyte-specific promoter of the chick type III collagen gene is activated by AP1 and is repressed in fibroblasts by a complex containing an LBP1-related protein. Nucleic Acids Res 27:4090-9

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