This Core will establish a national inception cohort of 1000 rheumatoid arthritis (RA) patients seen by 100 randomly selected rheumatologists within their first year of disease and will follow these patients using standard ARAMIS protocols with full Health Assessment Questionnaire (HAQ) administration each six months. Compared with prior attempts at building RA inception cohorts, this study will be (1) much larger, (2) contemporary, (3) broadly representative, (4) ethnically diverse, (5) encompass alternative management strategies, (6) contain DNA typing data (DRBI *0401 and *0404), (7) include standardized central laboratory determination of CRP and Rheumatoid Factor, (8) be over-sampled for Black and Hispanic patients, (9) consist of consecutively seen patients without exclusions, and (10) be maintained for long-term follow-up, including standardized reading of hand radiographs at 4 years of disease. The Core task builds upon investigator and staff skills at physician and patient recruitment and in maintenance of large data sets over the long-term. This inception cohort will provide a unique and powerful resource in support of Projects 1 and 2 as well as for future studies.

Project Start
1998-05-01
Project End
1999-04-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Chester Wasko, Mary; Dasgupta, Abhijit; Ilse Sears, Genevieve et al. (2016) Prednisone Use and Risk of Mortality in Patients With Rheumatoid Arthritis: Moderation by Use of Disease-Modifying Antirheumatic Drugs. Arthritis Care Res (Hoboken) 68:706-10
Wasko, Mary Chester M; Dasgupta, Abhijit; Hubert, Helen et al. (2013) Propensity-adjusted association of methotrexate with overall survival in rheumatoid arthritis. Arthritis Rheum 65:334-42
Chakravarty, Eliza F; Hubert, Helen B; Krishnan, Eswar et al. (2012) Lifestyle risk factors predict disability and death in healthy aging adults. Am J Med 125:190-7
Bruce, Bonnie; Fries, James F (2009) Rheumatologist perceptions of sources of health care disparities in minority rheumatoid arthritis patients. J Clin Rheumatol 15:145-7
Chakravarty, Eliza F; Hubert, Helen B; Lingala, Vijaya B et al. (2008) Reduced disability and mortality among aging runners: a 21-year longitudinal study. Arch Intern Med 168:1638-46
Hueber, Wolfgang; Tomooka, Beren H; Zhao, Xiaoyan et al. (2007) Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines. Ann Rheum Dis 66:712-9
Bruce, Bonnie; Fries, James F; Murtagh, Kirsten Naumann (2007) Health status disparities in ethnic minority patients with rheumatoid arthritis: a cross-sectional study. J Rheumatol 34:1475-9
Bruce, Bonnie; Lorig, Kate; Laurent, Diana (2007) Participation in patient self-management programs. Arthritis Rheum 57:851-4
Hueber, Wolfgang; Kidd, Brian A; Tomooka, Beren H et al. (2005) Antigen microarray profiling of autoantibodies in rheumatoid arthritis. Arthritis Rheum 52:2645-55
Bruce, B; Fries, J F (2005) The Arthritis, Rheumatism and Aging Medical Information System (ARAMIS): still young at 30 years. Clin Exp Rheumatol 23:S163-7

Showing the most recent 10 out of 53 publications