Abstract

The Biostatistics Support Core, previously called the Biometric Support Unit, has maintained the Bone Marrow Transplant Research Database since the beginning of the program project. The database contains information from all patients who have received marrow transplants at University of Minnesota Hospital, information gathered with careful quality control procedures. An experienced staff of data technicians gather relevant information from clinical and laboratory records and from attending physicians. The Biostatistics Support Core also provides statistical support for the project, assisting in the design of clinical trials and in the statistical analysis of clinical or retrospective studies, and performing additional statistical analyses requested by the investigators in the program project.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA021737-19
Application #
5206953
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Flynn, Catherine M; Hirsch, Betsy; Defor, Todd et al. (2007) Reduced intensity compared with high dose conditioning for allotransplantation in acute myeloid leukemia and myelodysplastic syndrome: a comparative clinical analysis. Am J Hematol 82:867-72
Orchard, Paul J; Blazar, Bruce R; Wagner, John et al. (2007) Hematopoietic cell therapy for metabolic disease. J Pediatr 151:340-6
Grewal, Satkiran S; Barker, Juliet N; Davies, Stella M et al. (2003) Unrelated donor hematopoietic cell transplantation: marrow or umbilical cord blood? Blood 101:4233-44
Wagner, John E; Barker, Juliet N; DeFor, Todd E et al. (2002) Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival. Blood 100:1611-8
Sladek, Norman E (2002) Leukemic cell insensitivity to cyclophosphamide and other oxazaphosphorines mediated by aldehyde dehydrogenase(s). Cancer Treat Res 112:161-75
Browne, P V; Weisdorf, D J; DeFor, T et al. (2000) Response to thalidomide therapy in refractory chronic graft-versus-host disease. Bone Marrow Transplant 26:865-9
Delforge, M; Boogaerts, M A; McGlave, P B et al. (1999) BCR/ABL- CD34(+)HLA-DR- progenitor cells in early chronic phase, but not in more advanced phases, of chronic myelogenous leukemia are polyclonal. Blood 93:284-92
Warwick, A B; Mertens, A C; Shu, X O et al. (1998) Outcomes following mechanical ventilation in children undergoing bone marrow transplantation. Bone Marrow Transplant 22:787-94
Katsanis, E; Weisdorf, D J; Miller, J S (1998) Activated peripheral blood mononuclear cells from patients receiving subcutaneous interleukin-2 following autologous stem cell transplantation prolong survival of SCID mice bearing human lymphoma. Bone Marrow Transplant 22:185-91
Arns da Cunha, C; Weisdorf, D; Shu, X O et al. (1998) Early gram-positive bacteremia in BMT recipients: impact of three different approaches to antimicrobial prophylaxis. Bone Marrow Transplant 21:173-80

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