The Core-General Laboratory Services provides services and performs laboratory work common to several projects. All human serum and tissue samples are logged in, stored and distributed to the appropriate laboratories through a centralized mechanism. Safety of laboratory personnel and procedures is regulated through this Core. Standard analyses, accepted procedures and assays that use commercial kits are performed. Laboratory procedures which are not routine or are experimental are described in the appropriate project.
Yamamoto, Toshiki; Litwin, Samuel; Zhou, Tianlun et al. (2002) Mutations of the woodchuck hepatitis virus polymerase gene that confer resistance to lamivudine and 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil. J Virol 76:1213-23 |
Zhu, Y; Yamamoto, T; Cullen, J et al. (2001) Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis. J Virol 75:311-22 |
Zhou, T; Saputelli, J; Aldrich, C E et al. (1999) Emergence of drug-resistant populations of woodchuck hepatitis virus in woodchucks treated with the antiviral nucleoside lamivudine. Antimicrob Agents Chemother 43:1947-54 |
Dube, D K; Dube, S; Erensoy, S et al. (1994) Serological and nucleic acid analyses for HIV and HTLV infection on archival human plasma samples from Zaire. Virology 202:379-89 |