Abstract

The core component provides support for centralized services and facilities that are used by the research groups participating in the program project. These core facilities include: computer facilities, animal quarters, oligonucleotide/oligopeptide synthesis and protein sequencing facility, flow cytometry facility, confocal and electron microscopy facilities. monoclonal antibody production facility, and cell culture and fly media production facilities. The facilities are operated by technical staff who assist investigators in their areas of specialization.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA041086-11
Application #
5207294
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Ferguson, Scott B; Blundon, Malachi A; Klovstad, Martha S et al. (2012) Modulation of gurken translation by insulin and TOR signaling in Drosophila. J Cell Sci 125:1407-19
Capra, John A; Laskowski, Roman A; Thornton, Janet M et al. (2009) Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure. PLoS Comput Biol 5:e1000585
Capra, John A; Singh, Mona (2008) Characterization and prediction of residues determining protein functional specificity. Bioinformatics 24:1473-80
Williams, Courtney M; Engler, Adam J; Slone, R Daniel et al. (2008) Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation. Cancer Res 68:3185-92
Banks, Eric; Nabieva, Elena; Chazelle, Bernard et al. (2008) Organization of physical interactomes as uncovered by network schemas. PLoS Comput Biol 4:e1000203
Sabourin, Michelle; Zakian, Virginia A (2008) ATM-like kinases and regulation of telomerase: lessons from yeast and mammals. Trends Cell Biol 18:337-46
Banks, Eric; Nabieva, Elena; Peterson, Ryan et al. (2008) NetGrep: fast network schema searches in interactomes. Genome Biol 9:R138
Klovstad, Martha; Abdu, Uri; Schupbach, Trudi (2008) Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint. PLoS Genet 4:e31
Clouse, K Nicole; Ferguson, Scott B; Schupbach, Trudi (2008) Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila. Dev Biol 313:713-24
Denef, Natalie; Chen, Yu; Weeks, Stephen D et al. (2008) Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. Dev Cell 14:354-64

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