Abstract

The Biostatistics Core Component of this Program Project Grant will provide overall guidance on study design, data processing and analysis, and statistical aspects of this research proposal in Drug Discovery. Collaborative research relationships already exist between staff members of the Biostatistics Core and the Principal Investigators of the various projects proposed. Biostatistical support appropriate to the needs of each of the individual research projects and Cores in this Program Project Grant will be provided by consultation with the respective Principal Investigators and Core Leaders.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA046560-08
Application #
6102423
Study Section
Project Start
1998-02-01
Project End
2000-01-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
8
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Wayne State University
Department
Type
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202

  Publications

Djuric, Zora; Vanloon, Glee; Radakovich, Katherine et al. (2008) Design of a Mediterranean exchange list diet implemented by telephone counseling. J Am Diet Assoc 108:2059-65
Corbett, Thomas H; White, Kathryn; Polin, Lisa et al. (2003) Discovery and preclinical antitumor efficacy evaluations of LY32262 and LY33169. Invest New Drugs 21:33-45
Polin, Lisa; White, Kathryn; Kushner, Juiwanna et al. (2002) Preclinical efficacy evaluations of XK-469: dose schedule, route and cross-resistance behavior in tumor bearing mice. Invest New Drugs 20:13-22
Poondru, Srinivasu; Parchment, Ralph E; Purohit, Vivek et al. (2002) Lack of in vitro-in vivo correlation of a novel investigational anticancer agent, SH 30. Invest New Drugs 20:23-33
Poondru, S; Zhou, S; Rake, J et al. (2001) High-performance liquid chromatographic method for the estimation of the novel investigational anti-cancer agent SR271425 and its metabolites in mouse plasma. J Chromatogr B Biomed Sci Appl 759:175-8
LoRusso, P M; Foster, B J; Wozniak, A et al. (2000) Phase I pharmacokinetic study of the novel antitumor agent SR233377. Clin Cancer Res 6:3088-94
Keyes, K A; Albella, B; LoRusso, P M et al. (2000) Cytotoxic chemotherapy regimens that increase dose per cycle (dose intensity) by extending daily dosing from 5 consecutive days to 28 consecutive days and beyond. Clin Cancer Res 6:2474-81
Corbett, T H; Panchapor, C; Polin, L et al. (1999) Preclinical efficacy of thioxanthone SR271425 against transplanted solid tumors of mouse and human origin. Invest New Drugs 17:17-27
Edelstein, M; Corbett, T; Valeriote, F (1998) In vitro screening model for the detection of agents active against myelogenous leukemia. Cancer Invest 16:303-8
Perni, R B; Wentland, M P; Huang, J I et al. (1998) Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives. J Med Chem 41:3645-54

Showing the most recent 10 out of 33 publications