Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA049089-06
Application #
2338344
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Type
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Girotti, A W; Korytowski, W (2000) Cholesterol as a singlet oxygen detector in biological systems. Methods Enzymol 319:85-100
Girotti, A W (1998) Lipid hydroperoxide generation, turnover, and effector action in biological systems. J Lipid Res 39:1529-42
Yamazaki, T; Sato, Y; Sieber, F (1997) Role of cytoprotective mechanisms in the photochemical purging of autologous bone marrow grafts. Exp Hematol 25:629-37
Geiger, P G; Korytowski, W; Lin, F et al. (1997) Lipid peroxidation in photodynamically stressed mammalian cells: use of cholesterol hydroperoxides as mechanistic reporters. Free Radic Biol Med 23:57-68
Lin, F; Girotti, A W (1997) Elevated ferritin production, iron containment, and oxidant resistance in hemin-treated leukemia cells. Arch Biochem Biophys 346:131-41
Kubo, Y; Sieber, F (1997) Photochemical purging of autologous bone marrow grafts: assessment of damage to stem cells and the microenvironment in long-term marrow cultures. Bone Marrow Transplant 20:27-31
Yamazaki, T; Sieber, F (1997) The alkyl-lysophospholipid, ET-18-OCH3 synergistically enhances the Merocyanine 540-mediated photoinactivation of leukemia cells: implications for the extracorporeal purging of autologous hematopoietic stem cells. Bone Marrow Transplant 19:113-9
Yamazaki, T; Sieber, F (1997) Effect of hypothermia on the merocyanine 540-mediated purging of hematopoietic cells. J Hematother 6:31-9
Singh, R J; Hogg, N; Joseph, J et al. (1996) Mechanism of nitric oxide release from S-nitrosothiols. J Biol Chem 271:18596-603
Korytowski, W; Geiger, P G; Girotti, A W (1996) Enzymatic reducibility in relation to cytotoxicity for various cholesterol hydroperoxides. Biochemistry 35:8670-9

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