Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
3P01CA054418-07S1
Application #
2645293
Study Section
Cancer Centers and Research Programs Review Committee (CCRP)
Project Start
1991-06-01
Project End
2001-04-30
Budget Start
1997-05-01
Budget End
1998-04-30
Support Year
7
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
005436803
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Carrano, Andrea C; Dillin, Andrew; Hunter, Tony (2014) A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans. Nat Commun 5:3772
Altarejos, Judith Y; Montminy, Marc (2011) CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12:141-51
Carrano, Andrea C; Liu, Zheng; Dillin, Andrew et al. (2009) A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature 460:396-9
Bres, Vanessa; Yoh, Sunnie M; Jones, Katherine A (2008) The multi-tasking P-TEFb complex. Curr Opin Cell Biol 20:334-40
Fryer, Christy J; White, J Brandon; Jones, Katherine A (2004) Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol Cell 16:509-20
Tutter, A; McAlpine, G S; Jones, K A (1999) Mechanism of chromatin recognition and transcriptional regulation by LEF-1 and the Wnt/Wg-responsive LEF-1:beta-catenin complex. Cold Spring Harb Symp Quant Biol 64:445-52
Bagga, R; Armstrong, J A; Emerson, B M (1998) Role of chromatin structure and distal enhancers in tissue-specific transcriptional regulation in vitro. Cold Spring Harb Symp Quant Biol 63:569-76
Bagga, R; Emerson, B M (1997) An HMG I/Y-containing repressor complex and supercoiled DNA topology are critical for long-range enhancer-dependent transcription in vitro. Genes Dev 11:629-39
Carlsson, P; Waterman, M L; Jones, K A (1993) The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells. Genes Dev 7:2418-30