Abstract

The Biostatistics portion of Core A is responsible for providing the essential program-wide expertise in experimental analysis and design, data acquisition, editing and management, data analysis, and results interpretation. It will provide the capabilities for, among other things, developing robust facilities for acquiring and managing project data, ensuring the integrity of the acquired data, developing procedures for estimating parameters of interest, assessing covariate significance and model appropriateness, integrating information from the various projects into a consistent whole, and investigating and comparing alternative approaches to data analysis and results interpretation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA055861-09A2
Application #
6617079
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2002-04-19
Project End
2007-01-31
Budget Start
Budget End
Support Year
9
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Lawrence Livermore National Laboratory
Department
Type
DUNS #
827171463
City
Livermore
State
CA
Country
United States
Zip Code
94550

  Publications

Turesky, Robert J; Goodenough, Angela K; Ni, Weijuan et al. (2007) Identification of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline: an abundant mutagenic heterocyclic aromatic amine formed in cooked beef. Chem Res Toxicol 20:520-30
Bogen, K T; Keating 2nd, G A; Chan, J M et al. (2007) Highly elevated PSA and dietary PhIP intake in a prospective clinic-based study among African Americans. Prostate Cancer Prostatic Dis 10:261-9
Keating, Garrett A; Bogen, Kenneth T; Chan, June M (2007) Development of a meat frequency questionnaire for use in diet and cancer studies. J Am Diet Assoc 107:1356-62
Keating, G A; Bogen, K T (2004) Estimates of heterocyclic amine intake in the US population. J Chromatogr B Analyt Technol Biomed Life Sci 802:127-33
Wogan, Gerald N; Hecht, Stephen S; Felton, James S et al. (2004) Environmental and chemical carcinogenesis. Semin Cancer Biol 14:473-86
Keating, G A; Bogen, K T (2001) Methods for estimating heterocyclic amine concentrations in cooked meats in the US diet. Food Chem Toxicol 39:29-43
Hatch, F T; Knize, M G; Colvin, M E (2001) Extended quantitative structure-activity relationships for 80 aromatic and heterocyclic amines: structural, electronic, and hydropathic factors affecting mutagenic potency. Environ Mol Mutagen 38:268-91
Bogen, K T; Enns, L; Hall, L C et al. (2001) Gel microdrop flow cytometry assay for low-dose studies of chemical and radiation cytotoxicity. Toxicology 160:5-10
Hatch, F T; Lightstone, F C; Colvin, M E (2000) Quantitative structure-activity relationship of flavonoids for inhibition of heterocyclic amine mutagenicity. Environ Mol Mutagen 35:279-99
Matsumoto, K; Tucker, J D (1998) Detection of structural chromosome damage in rat interphase cells using region-specific fluorescence in situ hybridization probes developed by microdissection. Mutat Res 421:179-90

Showing the most recent 10 out of 19 publications