Abstract

The research described under the various Projects will routinely utilize a number of specialized, state of the art, pieces of equipment. This usage will be more than can be accommodated by existing equipment already highly utilized and dedicated to other projects. Therefore, new equipment will have to be acquired. The Shared Equipment Core component will provide for several pieces of equipment which will be shared by all four projects within the program project. The acquisition and maintenance of this equipment as a shared resource is highly justified since all four projects will utilize a newly developed, highly sensitive technique called """"""""PCR-RNA phenotyping"""""""" for the analysis of tumor tissue. In addition to the shared equipment, provision is made for the maintenance of the shared equipment and for minimal levels of supplies for certain pieces of equipment.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA057596-05
Application #
2338799
Study Section
Project Start
Project End
Budget Start
1995-10-01
Budget End
1996-09-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Texas MD Anderson Cancer Center
Department
Type
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Wen, Kuang-Yi; Miller, Suzanne M; Stanton, Annette L et al. (2012) The development and preliminary testing of a multimedia patient-provider survivorship communication module for breast cancer survivors. Patient Educ Couns 88:344-9
Miliani de Marval, Paula L; Macias, Everardo; Conti, Claudio J et al. (2004) Enhanced malignant tumorigenesis in Cdk4 transgenic mice. Oncogene 23:1863-73
Rodriguez-Puebla, Marcelo L; Miliani de Marval, Paula L; LaCava, Margaret et al. (2002) Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. Am J Pathol 161:405-11
Stern, Mariana C; Benavides, Fernando; LaCava, Margaret et al. (2002) Genetic analyses of mouse skin tumor progression susceptibility using SENCAR inbred derived strains. Mol Carcinog 35:13-20
Miliani de Marval, P L; Gimenez-Conti, I B; LaCava, M et al. (2001) Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis. Am J Pathol 159:369-79
Benavides, F; Glasscock, E; Coghlan, L G et al. (2001) PCR-based microsatellite analysis for differentiation and genetic monitoring of nine inbred SENCAR mouse strains. Lab Anim 35:157-62
Benavides, F; Stern, M C; Glasscock, E et al. (2000) Microsatellite DNA variants between the inbred SENCAR mouse strains. Mol Carcinog 28:191-5
Coghlan, L G; Gimenez-Conti, I; Kleiner, H E et al. (2000) Development and initial characterization of several new inbred strains of SENCAR mice for studies of multistage skin carcinogenesis. Carcinogenesis 21:641-6
Rodriguez-Puebla, M L; LaCava, M; Miliani De Marval, P L et al. (2000) Cyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia. Am J Pathol 157:1039-50
Stern, M C; Benavides, F; Klingelberger, E A et al. (2000) Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression. Carcinogenesis 21:1297-301

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