Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA066570-05
Application #
6347372
Study Section
Project Start
2000-07-01
Project End
2002-06-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
2000
Total Cost
$113,422
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sonnenberg, Gregory F; Mangan, Paul R; Bezman, Natalie A et al. (2010) Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production. Blood 115:2186-95
Zhu, Nongliao; Ramirez, Luis M; Lee, Rosaline L et al. (2002) CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway. J Immunol 168:744-54
Hostager, Bruce S; Bishop, Gail A (2002) Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b. J Immunol 168:3318-22
Shen, Weiyin; Waldschmidt, Marianella; Zhao, Xiuqin et al. (2002) Antitumor mechanisms of oligodeoxynucleotides with CpG and polyG motifs in murine prostate cancer cells: decrease of NF-kappaB and AP-1 binding activities and induction of apoptosis. Antisense Nucleic Acid Drug Dev 12:155-64
Brown, Kevin D; Hostager, Bruce S; Bishop, Gail A (2002) Regulation of TRAF2 signaling by self-induced degradation. J Biol Chem 277:19433-8
Bishop, G A; Ramirez, L M; Baccam, M et al. (2001) The immune response modifier resiquimod mimics CD40-induced B cell activation. Cell Immunol 208:9-17
Brown, K D; Hostager, B S; Bishop, G A (2001) Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). J Exp Med 193:943-54
Catlett, I M; Xie, P; Hostager, B S et al. (2001) Signaling through MHC class II molecules blocks CD95-induced apoptosis. J Immunol 166:6019-24
Busch, L K; Bishop, G A (2001) Multiple carboxyl-terminal regions of the EBV oncoprotein, latent membrane protein 1, cooperatively regulate signaling to B lymphocytes via TNF receptor-associated factor (TRAF)-dependent and TRAF-independent mechanisms. J Immunol 167:5805-13
Myers, L P; Krieg, A M; Pruett, S B (2001) Bacterial DNA does not increase serum corticosterone concentration or prevent increases induced by other stimuli. Int Immunopharmacol 1:1605-14

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