The goal of the Data Management and analysis Core is to provide data management and statistical analysis Services. A broad range of services and collaboration will be provided. Core members will serve as true collaborators, having been involved from the conception of each Project through its design. Core members will continue to be involved in all projects through assistance and advising regarding data collection, analysis, summarizing the results, and manuscript preparation. The Data Management and Analysis core will provide the following services: 1. Data management a. Implement a data management framework to facilitate statistical analysis, through establishing and maintaining interaction among the Core Leader, Biostatistician, Programmer Analyst, and Medical Informatician. b. Determine Project-specific data management requirements and refine those as needed. c. Design and implement procedures for enrolling and tracking subjects and tracking the flow of data through the various phases of the projects. d. Design and implement procedures for input forms design and coding, data entry and validation, acquisition of data from existing sources and database systems, quality assurance, and reporting of data. e. Design, test, implement, and maintain database structures and application programs. 2. Biostatistics a. Advise on study design issues as the studies evolve. b. Implement analytical methods defined in the Project-specific proposals. c. Conduct interim analyses, and assist with writing interim reports. d. Conduct final analyses and assist with preparation for a writing of final reports, abstracts, manuscripts, and future research proposals. e. Conduct exploratory analyses that may lead to generation of new hypotheses.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA075434-03
Application #
6203434
Study Section
Project Start
1999-07-21
Project End
2000-06-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Kanetsky, Peter A; Swoyer, Jennifer; Panossian, Saarene et al. (2002) A polymorphism in the agouti signaling protein gene is associated with human pigmentation. Am J Hum Genet 70:770-5
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Rebbeck, Timothy R; Kanetsky, Peter A; Walker, Amy H et al. (2002) P gene as an inherited biomarker of human eye color. Cancer Epidemiol Biomarkers Prev 11:782-4

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