Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA078048-06A1
Application #
6989478
Study Section
Subcommittee G - Education (NCI)
Project Start
2004-05-24
Project End
2009-04-30
Budget Start
2004-05-24
Budget End
2005-04-30
Support Year
6
Fiscal Year
2004
Total Cost
$290,375
Indirect Cost
Name
Harvard University
Department
Type
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115
Shi, Jue; Mitchison, Timothy J (2017) Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic. Endocr Relat Cancer 24:T83-T96
Bradner, James E; West, Nathan; Grachan, Melissa L et al. (2010) Chemical phylogenetics of histone deacetylases. Nat Chem Biol 6:238-243
Gatlin, Jesse C; Matov, Alexandre; Danuser, Gaudenz et al. (2010) Directly probing the mechanical properties of the spindle and its matrix. J Cell Biol 188:481-9
Tolopko, Andrew N; Sullivan, John P; Erickson, Sean D et al. (2010) Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities. BMC Bioinformatics 11:260
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Maresca, Thomas J; Groen, Aaron C; Gatlin, Jesse C et al. (2009) Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity. Curr Biol 19:1210-5
Kawada, Junichi; Zou, Ping; Mazitschek, Ralph et al. (2009) Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis. J Biol Chem 284:17102-9
Gatlin, Jesse C; Matov, Alexandre; Groen, Aaron C et al. (2009) Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. Curr Biol 19:287-96
Huang, Hsiao-Chun; Shi, Jue; Orth, James D et al. (2009) Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell 16:347-58
Birmingham, Amanda; Selfors, Laura M; Forster, Thorsten et al. (2009) Statistical methods for analysis of high-throughput RNA interference screens. Nat Methods 6:569-75

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