) The Informatics Core will provide support and expertise for the data management requirements of the projects and cores. In addition, the Core will provide statistical support for planned and new projects and trials. The specific responsibilities of the Informatics Core are: (1) to provide the statistical support required to accomplish the specific aims of the individual projects; (2) to assist in the design and analysis of new projects and studies arising from the results of the proposed studies; (3) to assist individual investigators and core facilities in the collection and maintenance of required data; (4) to facilitate the exchange of information and data between projects; (5) to provide for rigorous data management, quality assurance, auditing procedures, and confidentiality of clinical trial data; (6) to coordinate the data acquisition and biostatistical analysis and audit planning for the Internal Data Monitoring Committee.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA078778-04
Application #
6591274
Study Section
Subcommittee G - Education (NCI)
Project Start
2002-05-07
Project End
2003-04-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
4
Fiscal Year
2002
Total Cost
$279,549
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Pataer, Apar; Kalhor, Neda; Correa, Arlene M et al. (2012) Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy. J Thorac Oncol 7:825-32
Kadowaki, Yoshihiko; Chari, Nikhil S; Teo, Albert E K et al. (2011) PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells. Apoptosis 16:627-35
Pataer, Abujiang; Swisher, Stephen G; Roth, Jack A et al. (2009) Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. Cancer Biol Ther 8:245-52
Pataer, Abujiang; Chada, Sunil; Roth, Jack A et al. (2008) Development of Ad-mda7/IL-24-resistant lung cancer cell lines. Cancer Biol Ther 7:103-8
Pataer, Abujiang; Hu, Wenxian; Xiaolin, Lu et al. (2008) Adenoviral endoplasmic reticulum-targeted mda-7/interleukin-24 vector enhances human cancer cell killing. Mol Cancer Ther 7:2528-35
Pataer, A; Bocangel, D; Chada, S et al. (2007) Enhancement of adenoviral MDA-7-mediated cell killing in human lung cancer cells by geldanamycin and its 17-allyl- amino-17-demethoxy analogue. Cancer Gene Ther 14:12-8
Peng, Henry H; Wu, Shuhong; Davis, John J et al. (2006) A rapid and efficient method for purification of recombinant adenovirus with arginine-glycine-aspartic acid-modified fibers. Anal Biochem 354:140-7
Pataer, A; Fanale, M A; Roth, J A et al. (2006) Induction of apoptosis in human lung cancer cells following treatment with amifostine and an adenoviral vector containing wild-type p53. Cancer Gene Ther 13:806-14
Li, Zhongkui; Niu, Jiangong; Uwagawa, Tadashi et al. (2005) Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response. J Biol Chem 280:16843-50
Sclabas, Guido M; Fujioka, Shuichi; Schmidt, Christian et al. (2005) Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. Clin Cancer Res 11:440-9

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