The Administrative Core Component D serves three important purposes. The first purpose of this Administrative Core is to provide all Projects and shared Cores with appropriate administrative support to efficiently carry out the scientific goals of the Program Project. These essential services are not provided by the Massachusetts General Hospital. The key responsibilities of Core D include: (i) general administration;(ii) fiscal oversight (budgeting, purchasing);(iii) communication and coordination of data flow;(iv) seminar series coordination and travel arrangements;and (v) support with preparation of manuscripts and reports. The second purpose of this core component is to closely monitor the activities of the Cox-7 Animal Colony, which is the chief facility of Core C. The Surgical and Animal Core (Core C) requires additional administrative effort for the following reasons: (i) it must adhere closely to additional regulations for breeding and maintaining animals;and (ii) it is responsible for the coordination and submission of all animal protocols. The third purpose of Core D is to provide the overall scientific direction for the Program Project and ensure optimal use of the shared resources. This is achieved by close interaction with: (i) the Scientific Steering Committee;(ii) External and Internal Scientific Advisory Boards;and (iii) Consultants/Collaborators for individual projects and cores. These groups regularly evaluate the progress and agenda of the PPG. The input of these advisory groups is discussed at the monthly Scientific Steering Committee Meetings and is incorporated in specific projects and cores.

Public Health Relevance

This Administrative Core will provide all Projects and Cores with appropriate administrative support to efficiently carry out the scientific goals of the Program Project. Core D will closely monitor the activities of the Cox-7 Animal Colony. Core D will also provide the overall scientific direction for the Program Project.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA080124-13
Application #
8657999
Study Section
Special Emphasis Panel (ZCA1-RPRB-O)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
13
Fiscal Year
2014
Total Cost
$187,264
Indirect Cost
$79,641
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Jain, Rakesh K; Batista, Ana (2018) A Physical View of Cancer. Trends Cancer 4:257
Li, Suyan; Kumar T, Peeyush; Joshee, Sampada et al. (2018) Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Res 28:221-248
Carr, Jessica A; Franke, Daniel; Caram, Justin R et al. (2018) Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green. Proc Natl Acad Sci U S A 115:4465-4470
Fukumura, Dai; Kloepper, Jonas; Amoozgar, Zohreh et al. (2018) Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nat Rev Clin Oncol 15:325-340
Pereira, Ethel R; Kedrin, Dmitriy; Seano, Giorgio et al. (2018) Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice. Science 359:1403-1407
Dixon, Karen O; Schorer, Michelle; Nevin, James et al. (2018) Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. J Immunol 200:3000-3007
Samaha, Heba; Pignata, Antonella; Fousek, Kristen et al. (2018) A homing system targets therapeutic T cells to brain cancer. Nature 561:331-337
Binnewies, Mikhail; Roberts, Edward W; Kersten, Kelly et al. (2018) Understanding the tumor immune microenvironment (TIME) for effective therapy. Nat Med 24:541-550
Nia, Hadi T; Datta, Meenal; Seano, Giorgio et al. (2018) Quantifying solid stress and elastic energy from excised or in situ tumors. Nat Protoc 13:1091-1105
Ina Ly, K; Vakulenko-Lagun, Bella; Emblem, Kyrre E et al. (2018) Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI. Sci Rep 8:17062

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