CORE 1: PEPTIDE SYNTHESIS This core provides a central peptide synthesis resource for the program. The individual programs each depend on the use of synthetic peptides. Establishing in-house expertise for generating synthetic peptides is essential to the success of this program.
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| Mitra, Sayantan; Duggineni, Srinivas; Koolpe, Mitchell et al. (2010) Structure-activity relationship analysis of peptides targeting the EphA2 receptor. Biochemistry 49:6687-95 |
| Järvinen, Tero A H; Ruoslahti, Erkki (2010) Target-seeking antifibrotic compound enhances wound healing and suppresses scar formation in mice. Proc Natl Acad Sci U S A 107:21671-6 |
| Richardson, Robyn D; Ma, Gil; Oyola, Yatsandra et al. (2008) Synthesis of novel beta-lactone inhibitors of fatty acid synthase. J Med Chem 51:5285-96 |
| Jarvinen, Tero A H; Ruoslahti, Erkki (2007) Molecular changes in the vasculature of injured tissues. Am J Pathol 171:702-11 |
| Zhang, Lianglin; Giraudo, Enrico; Hoffman, Jason A et al. (2006) Lymphatic zip codes in premalignant lesions and tumors. Cancer Res 66:5696-706 |
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| Zhang, Lianglin; Hoffman, Jason A; Ruoslahti, Erkki (2005) Molecular profiling of heart endothelial cells. Circulation 112:1601-11 |
| Komatsu, Masanobu; Ruoslahti, Erkki (2005) R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis. Nat Med 11:1346-50 |
| Ruoslahti, E; Duza, T; Zhang, L (2005) Vascular homing peptides with cell-penetrating properties. Curr Pharm Des 11:3655-60 |
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