Core A is responsible for cohort follow-up and database maintenance in the Nurses'Health Study.
The specific aims for this core are as follows: 1) Develop and mail biennial follow-up questionnaires to cohort participants 2) Process returned questionnaires and verify responses 3) Compile databases of exposure data 4) Trace lost participants and maintain an updated name and address file 5) Sustain high cohort participation Under the direction of Diane Feskanich, ScD, Core A develops and designs the questionnaire for biennial follow-up of study participants. Questionnaire design incorporates input from all investigators on the Program Project, as well as other collaborating investigators, through bi-weekly meetings. New questions are pilot tested and follow-up methods are refined to address the needs of the cohort members. Returned questionnaires are checked for completeness, optically scanned, and verified for errors. Over 80,000 questionnaires are returned in every follow-up cycle. Core A uses a range of methods to trace participants and to maintain a high 90% response rate. Returned questionnaires are digitally imaged and stored on DVD, from which they are easily retrievable. Exposure data from the questionnaires are complied into databases and variables are derived and documented for use by investigators. This includes maintenance of nutrient intakes derived from the food frequency portion of the questionnaire. Diseases reported on the questionnaires are passed to Core B for confirmation.

Public Health Relevance

Core A activities are critical for gathering exposure and disease information and for maintaining follow-up in the Nurses'Health Study and hence for maintaining the validity of all analyses conducted in Projects 1-4. By extension, this Core is vital to our ability to find ways to prevent cancer Incidence and improve survival in women.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA087969-11
Application #
7786697
Study Section
Special Emphasis Panel (ZCA1-RPRB-7 (O1))
Project Start
2010-04-01
Project End
2015-03-31
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
11
Fiscal Year
2010
Total Cost
$675,663
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
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